Skip to content

Tisuacryl® in esophageal surgery

Use of tissue adhesive Tisuacryl® in the prevention of dehiscences and fistulas of esophageal anastomosis with segments of stomach, jejunum and colon

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
RPCEC
Registry ID
RPCEC00000045
Enrollment
58
Registered
2008-09-12
Start date
1999-02-03
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer or benign stenosis

Interventions

Esophagueal anastomosis Experimental Group: Partial excision of the esophagus was done by surgical techniques established in the Surgery Service of the Hospital Calixto García (transhiatal esophagecto
Esophagectomy
Anastomosis, Surgical

Sponsors

Center of Biomaterials of Havana University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Adult patients, between 18 and 70 years old Patients of both sexes Patients that gave their informed consent to participate in the study Patients that fulfill one of the following diagnostic criteria: Resectable esophageal cancer phases I, II or III Benignant stenosis that requires esophageal resection with or without portions of the stomach. Both conditions were diagnosed by endoscopic techniques and biopsy.

Exclusion criteria

Exclusion criteria: Patient whose health conditions do not permit surgical treatment Patients with hypersensitivity to cyanoacrylates Patients with mental illness or severe psychological disorders, Pregnant women or during lactation Patients who don’t consent to participate in the study

Design outcomes

Primary

MeasureTime frame
Presence of fistula, 25 days

Secondary

MeasureTime frame
Time of appearance of fistula, up to 90 days Stenosis of the anastomosis, 90 days Adverse effects, up to 90 days

Countries

Cuba

Contacts

Public ContactDr. Rosa Guerra Bretaña

Center or Biomaterials of Havana University

mayelin@biomat.uh.cu

Outcome results

None listed

Source: RPCEC (via WHO ICTRP) · Data processed: Apr 4, 2026