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Evaluation of dental sensitivity after bleaching using a bleaching gel with bioglass nanoparticles

Effect of hydrogen peroxide 35% bioglass nanoparticles-containing on tooth sensitivity for in-office bleaching: A randomized triple blind clinical study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-9zzg4d
Enrollment
Unknown
Registered
2019-11-15
Start date
2019-03-14
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth Bleaching

Interventions

Experimental group: 66 volunteers will receive application of a hydrogen peroxide whitening gel containing bioglass nanoparticles on their teeth. There will be two sessions, with an interval of 7 days
Other

Sponsors

Universidade Estadual de Ponta Grossa
Lead Sponsor
Universidade Estadual de Ponta Grossa
Collaborator

Eligibility

Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age between 18 and 30 years, regardless of gender; have a voluntary interest in undergoing aesthetic treatment for teeth whitening; agree to the Informed Consent Form (ICF); present from first to first molar, in the upper and lower arches, healthy, without caries lesion and / or restoration with extension to the buccal face of the teeth; present teeth with initial color A2 or higher, according to the Classic Vita scale; present good oral health (absence of injury or any type of alteration suggestive of pathology) and systemic; have good oral hygiene and periodontal health (absence of gingivitis and periodontitis, the latter being considered as the presence of two or more teeth with 3mm probing depth).

Exclusion criteria

Exclusion criteria: Patients who have already undergone teeth whitening treatment; patients with self-reported dental sensitivity (spontaneous and / or provoked); have teeth with severe color change (staining by tetracycline, fluorosis, hypoplastic; and / or traumatized; have teeth endodontically treated, among which will undergo the whitening procedure; are undergoing medical treatment or are using controlled medication; 6. Are using anti-inflammatory and / or analgesic medications, having recessions of gingival tissue and exposure of dentine tissue in the cervical region, having functional and painful symptoms of the mandibular temporomandibular joint (TMJ), having teeth with clinically visible cracks or fracture; orthodontic appliance or any type of prosthetic restoration, female patients who are pregnant or breastfeeding.

Design outcomes

Primary

MeasureTime frame
Expected Outcome: To assess the absolute risk of in-office bleaching sensitivity of 35% Hydrogen Peroxide gel with the addition of bioglass nanoparticles (Bio) compared with conventional 35% Hydrogen Peroxide gel in adult patients.

Secondary

MeasureTime frame
To evaluate bleaching effectiveness by subjective method using Vita Classical (Vita Lumin, Vita Zahnfabrik, Bad Säckingen, Germany), Vita Bleachedguide 3D-Master (BG, Vita Zahnfabrik, Bad Säckingen, Germany) and objective method using Vita Easy Shade spectrophotometer (Vita Zahnfabrik, Bad Säckingen, Germany), Conventional 35% Hydrogen Peroxide bleaching gel and 35% Hydrogen Peroxide (Bv) with in-office bleaching technique (in- office).

Countries

Brazil

Contacts

Public ContactAlessandro Loguércio

Universidade Estadual de Ponta Grossa

aloguercio@hotmail.com+55(42)3220-3740

Outcome results

None listed

Source: REBEC (via WHO ICTRP)