Sialorrhea
Conditions
Interventions
This is a randomized, crossover, placebo-controlled, triple-blind clinical trial in which sixteen adult participants with complete permanent dentition took part in two experimental sessions with a one
Sponsors
Universidade Estadual de Ponta Grossa-UEPG
Universidade Estadual de Ponta Grossa-UEPG
Eligibility
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: age 18–65 years; American Society of Anesthesiologists ASA physical status I; fully dentate ; 28 permanent teeth excluding third molars; with no untreated caries or extensive restorations; and good oral and periodontal health.
Exclusion criteria
Exclusion criteria: known allergy or hypersensitivity to atropine or placebo components; current use of medications affecting salivary flow; cholinergic or anticholinergic agents); diagnosis of xerostomia or salivary gland dysfunction; pregnancy or lactation; significant systemic or neurological conditions affecting saliva production; orthodontic appliances or fixed prostheses; extensive or defective restorations impacting scanning; active oral lesions or infections; and strong gag reflex or intolerance to intraoral procedures
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It was expected that the use of one percent sublingual atropine would improve the accuracy of intraoral scanning, assessed by trueness and measured by the root mean square error obtained from the superimposition of the intraoral scan of the mandibular arch with a digital reference model, when compared with the placebo condition;A statistically significant improvement in intraoral scanning accuracy was observed in the condition using one percent sublingual atropine, demonstrated by a reduction in root mean square error values when compared with the placebo condition | — |
Secondary
| Measure | Time frame |
|---|---|
| It was expected that the use of one percent sublingual atropine would result in a reduction in salivary flow measured by a gravimetric method using cotton rolls, as well as a decrease in the time required to perform intraoral scanning and an improvement in participant comfort during the procedure;A significant reduction in salivary flow was observed after the use of one percent sublingual atropine compared with placebo, associated with a decrease in intraoral scanning time and improved comfort perception reported by participants during the procedure | — |
Countries
Brazil
Contacts
Public Contactcynthia egg
Universidade Estadual de Ponta Grossa-UEPG
Outcome results
None listed