Recurrent depressive disorder
Conditions
Interventions
Low-cost physical exercise programs will be implemented in or around the partner UBS. The intervention will be performed for 6 months (24 weeks), twice a week (on non-consecutive days), with sessions
and 2) aerobic group with high motor complexity (coordinative) (GAC) and 3) monitoring group (control).
1) The GA will only perform continuous walking exercises for 40 minutes being preceded and com
Other
G11.427.590.530.698.277
E02.760.169.063.500.387
Sponsors
Universidade de São Paulo - Escola de educação Física e esporte
Fundação de Amparo a Pesquisa do Estado de São Paulo
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Secretaria estadual de saúde de São Paulo
Ministério da saúde
Eligibility
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: Have a diagnosis of major depressive episode (single or recurrent episode by the Mini International Neuropsychiatric Interview (MINI), evaluated by a psychiatrist-trained evaluator; use of pharmacological treatment for mental health (use of anxiolytic drugs or antidepressants); did not participate in a systematic exercise program in the last 6 months and be able to perform systematic physical exercise (medical authorization); be over 40 years of age; do not have chronic degenerative diseases, dementias (score <23 in the Mini Mental State Examination), joint or muscle injuries that prevent him from carrying out systematized physical exercises.
Exclusion criteria
Exclusion criteria: Not being willing to participate in evaluations; Not having availability of participation of interventions that will occur on weekdays; make use of walking sticks, crutches or other support that hinder the practice of physical exercise.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average difference of 6 points on the Depression Rating Scale Montgomery-Asberg - MADRS in favor of physical exercise groups. | — |
Secondary
| Measure | Time frame |
|---|---|
| Cognitive function: Front evaluation battery, Processing speed, Function and memory - 10% increase in performance in favor of physical exercise groups.; MOca - Increase of 2 points in favor of physical exercise groups; Stroop test - decrease in 2 seconds in the execution of the test in favor of physical exercise groups. The Frontal Evaluation Battery [36] is a brief tool designed to evaluate executive functions. This instrument takes approximately 10 minutes to administer its six items: (i) similarities (conceptualization) - explores abstract reasoning by presenting pairs of objects of the same semantic category; (ii) lexical fluency (mental flexibility) - evaluates self-organization, strategy and change, generating as many words as possible beginning with a certain letter; (iii) series of engines - explores scheduling and engine planning by running the Luria (palm side) series; (iv) conflicting instructions - exploits the sensitivity to interference, giving the opposite response to that of the examiner; (v) go / no-go - evaluates inhibitory control and impulsivity; and (vi) grip behavior - evaluates the ability to spontaneously inhibit grip. A maximum score of 18 is obtained by adding the score to each of the six items, which are scored between 0 and 3. Each of the six items evaluates different cognitive and behavioral domains involved in different neural networks. The Trail A and B test was proposed in the mid-last century [37] to assess visual tracking, attention, mental flexibility and motor function [71]; They were used to assess the effect of physical exercise on executive functions [24]. It consists of two sections (A and B): circles with numbers (1-25) (Session A) and numbers (1-13) and letters (A - L) (session B). The evaluator should draw lines with a pencil or pen to connect the circles in an ascending pattern (Session A) and increasing pattern, but performing the alternation between numbers and letters (that is, 1-A-2-BC-3, etc.). - Session B). | — |
Countries
Brazil
Contacts
Public ContactLucas Neves
Universidade de São Paulo - Escola de educação Física e esporte
Outcome results
None listed