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The influence of the type of anesthesia on the appearance of changes in brain activity after video surgeries, in which the patient's head is tilted downwards

Analysis of two anesthetic techniques in the appearance of postoperative delirium of cancer patients submitted to surgeries of videolaparoscopy in trendelenburg position

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-9yrqwh
Enrollment
Unknown
Registered
2018-03-02
Start date
2017-10-18
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium

Interventions

Patients will be divided into 2 groups (65 patients each): 1) Balanced general anesthesia. 2) Balanced general anesthesia associated with subarachnoid block with 0.5% hyperbaric bupivacaine (3ml). All
Procedure/surgery

Sponsors

Fundação Antônio Prudente
Lead Sponsor
A.C. Camargo Cancer Center
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: patients from the AC Camargo Cancer Center; aged 18 years or over; American Society of Anesthesia (ASA), less than 3, submitted to elective laparoscopic surgery in a Trendelenburg position, minimum period of 2 hours and who agree to sign the free and informed consent form.

Exclusion criteria

Exclusion criteria: Absolute contraindication and related to spinal anesthesia; with difficult airway prediction with possibility of awake intubation; With previous diagnosis of: cognitive disorder and / or depression; chronic use of benzodiazepines (use during the last 12 weeks); referred to perform the postoperative ICU; with diagnosis of anemia (Hemoglobin G3a (glomerular filtration rate 30 kg / m2);with history of nausea / vomiting in previous anesthetic procedures; with diagnosis of malignant hyperthermia.

Design outcomes

Primary

MeasureTime frame
Incidence of postoperative delirium with general anesthesia + spinal morphine. Delirium assessed by CAM scale Confusion Assemenment Method) e RASS (Richmond Agitation Sedation Scale );Incidence of postoperative delirium with general anesthesia + subarachnoid block. Delirium assessed by CAM scale Confusion Assemenment Method) e RASS (Richmond Agitation Sedation Scale )

Secondary

MeasureTime frame
Secondary outcomes are not expected

Countries

Brazil

Contacts

Public ContactGiane Nakamura

Fundação Antônio Prudente

gianenakamura@hotmail.com55-11-21895000

Outcome results

None listed

Source: REBEC (via WHO ICTRP)