Stomatitis
Conditions
Interventions
The sample will be composed of 17 patients, divided into two groups: Group I (test group) will receive 2g of glutamine diluted in 15ml of saline and Group II (control group) will use 15ml of 0.9% sali
Drug
Sponsors
Universidade Estadual da Paraíba
Daliana Queiroga de Castro Gomes
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients of both sexes; regardless of ethnicity; over 18 years of age; undergoing head and neck radiotherapy with at least half of the oral mucosa area included in the radiation fields.
Exclusion criteria
Exclusion criteria: Patients submitted to palliative RT; those who could not open their mouths; and those who used prophylactic topical drugs or mouth rinse; and those who presented Karnofsky Performance Status<70 were excluded; Interruption of use for just one day and not coming to the dental evaluation resulted in the elimination of the patient from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected to meet 25% of group I patients developed grade 2 mucositis, while no group II was found in 88.9% of patients; The difference between the two groups being statistically significant (p = 0.003). | — |
Secondary
| Measure | Time frame |
|---|---|
| In group I, the occurrence of grade 2 mucositis decreased over the weeks of radiotherapy, while in group II, the grade 1, 2 and 3 mucositis increased during these weeks. | — |
Countries
Brazil
Contacts
Public ContactDaliana Queiroga de Castro Gomes
Universidade Estadual da Paraíba
Outcome results
None listed