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Laser therapy in the periodontal treatment of patients with chronic kidney disease

Antimicrobial photodynamic therapy in the periodontal treatment of patients with chronic kidney disease

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-9yr3qb8
Enrollment
50
Registered
2026-05-22
Start date
2024-05-14
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis. Renal Insufficiency Chronic Periodontitis

Interventions

This clinical study will include two groups of participants, totaling approximately 50 volunteers, distributed as follows: test group (number = 25), patients with chronic kidney disease undergoing dia
at least 30% of sites with probing depth and clinical attachment level equal to or greater than 4 mm, associated with bleeding on probing. Participants in the control group must meet the same criteria

Sponsors

Universidade Federal do Paraná
Lead Sponsor
Universidade Federal do Paraná
Collaborator
Setor de Ciências da Saúde da Universidade Federal do Paraná
Collaborator

Eligibility

Age
30 Years to 80 Years

Inclusion criteria

Inclusion criteria: Volunteers of both sexes; and with the age range from 30 to 80 years. Have at least 10 teeth in the mouth, excluding teeth indicated for extraction. Be patients with chronic kidney disease (test group). Be patients without chronic kidney disease (control group). Have at least 3 teeth with at least 1 interproximal site, not contiguous, with Probing Depth and Clinical Attachment Level of 5 mm, as well as at least 30% of sites with Probing Depth and Clinical Attachment Level of 4 mm and Bleeding on Probing. Patients in the control group will have the same inclusion criteria, except for the presence of chronic kidney disease, and will be matched according to age (plus or minus 3 years) and gender

Exclusion criteria

Exclusion criteria: Pregnant women. Patients who have undergone periodontal treatment in the last six months. Patients who smoke or have smoked within the last five years

Design outcomes

Primary

MeasureTime frame
It is expected that there will be a reduction in probing depth of at least 15%, as assessed by periodontal examination after 90 and 182 days compared with baseline

Secondary

MeasureTime frame
It has no secondary outcome

Countries

BR

Contacts

Public ContactGabriela Izumi

Universidade Federal do Paraná

gabriela.izumi@ufpr.br+55 (41) 991967109

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Jun 11, 2026