Noise induced Hearing Loss
Conditions
Interventions
Determine whether the noise is harmful to dental students auditory system and if magnesium supplementation as a single 200 mg dose,(use of Medicines in Divergent Situations of the Bull - off-label use
Drug
Other
D12.125.067.500.700
Sponsors
Setor de saúde auditiva do Hospital Universitário de Brasília
Setor de saúde auditiva do Hospital Universitário de Brasília
Eligibility
Age
17 Years to 30 Years
Inclusion criteria
Inclusion criteria: Students aged 17 to 30 years; presenting no self-reported comorbidities; had no previous history of using ototoxic drugs; no amplified music exposure in the past 24 hours before the investigation; no history of middle ear infection; no auditory complaints; and a normal serum magnesium level evaluated at a maximum of 1 month before the investigation
Exclusion criteria
Exclusion criteria: Comorbidities; previous history of using ototoxic drugs; previous exposure to music in the last 24 hours;auditory complaints; no normal serum magnesium level evaluated at a maximum of 1 month before the investigation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find changes of the DPOAE parameters in the dental students, who received the placebo medication, after approximately 3 hours of exposure; It is expected to find no changes of the DPOAE parameters in the dental students, who received 200 mg dose of magnesium after approximately 3 hours of exposure. ; The monitored noise did not change the DPOAE parameters in the dental students after approximately 3 hours of exposure. Even though a single 200 mg dose of magnesium did not produce any side effects, no effect was observed in hearing preservation in this investigation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected | — |
Countries
Brazil
Contacts
Public ContactISABELLE SILVA
Setor de saúde auditiva do Hospital Universitário de Brasília
Outcome results
None listed