Non-insulin-dependent diabetes mellitus
Conditions
Interventions
Periodized strength training group: 20 individuals with type 2 diabetes will undergo supervised strength training 3 times per week. Eight strength exercises will be performed during each training sess
(Day 2) 3 sets of 10 maximum repetitions with recovery of 80 seconds
And 3 sets of 6 maximum reps with 120 seconds recovery. Non-periodized strength training group: 20 individuals with type 2 diabetes undergo supervised strength training 3 times per week. Eight strengt
Behavioural
G11.427.590.530.698.277
E02.779.483
Sponsors
Universidade Federal do Rio Grande do Norte - UFRN
Hospital Universitário Onofre Lopes - HUOL
Eligibility
Inclusion criteria
Inclusion criteria: Age between 30 and 70 years; body mass index between 25.0 and 39.9 kg/m2; diagnosis of type 2 diabetes for a period equal or greater than 1 year; insufficiently active or sedentary
Exclusion criteria
Exclusion criteria: Clinically unstable Diabetes (change in medication within the last two months); insulin-dependent; history of stroke, neuropathy or advanced retinopathy; pregnant or suspected pregnancy; contraindication for magnetic resonance imaging, according to the list available at: http://www.mrisafety.com/; severe musculoskeletal problems that limit the practice of physical activity; health problems that may interfere with the study protocols or safety during exercise; classified as "risk" for cardiovascular diseases; not submitting medical authorization to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of the glycated hemoglobin level after 16 weeks of strength training, verified by blood plasma analysis, from the observation of a variation of at least 0.6% in the pre- and post-intervention measurements | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of the body composition after 16 weeks of strength training, verified through total abdomen visceral adipose tissue, thigh adipose tissue, thigh muscle tissue, fat mass, and fat-free mass, from the observation of a significant change in pre- and post-intervention measurements;Improvement of the metabolic aspects after 16 weeks of strength training, verified through 24-hour glycemic curve and variability, fasting glucose, postprandial glycaemia, plasm insulin, insulin resistance, and blood lipids, from the observation of a significant change in pre- and post-intervention measurements;Improvement of the cardiovascular aspects after 16 weeks of strength training, verified through 24-hour blood pressure, resting blood pressure, and resting heart rate variability, from the observation of a significant change in pre- and post-intervention measurements;Increase of the cardiorespiratory fitness after 16 weeks of strength training, verified through one-mile walk/run test, from the observation of a significant change in pre- and post-intervention measurements;Increase of the muscle strength after 16 weeks of strength training, verified through one-repetition maximum test, from the observation of a significant change in pre- and post -intervention measurements;Increase of the muscle quality after 16 weeks of strength training, verified through relationship between thigh muscle mass and lower limb muscle strength, from the observation of a significant change in the pre- and post-intervention measurements;Increase of the resting metabolic rate after 16 weeks of strength training, verified through indirect calorimetry, from the observation of a significant change in pre- and post-intervention measurements;Improvement of the quality of life after 16 weeks of strength training, verified through quality of life questionnaire, from the observation of a significant change in the pre- and post-intervention measurements;Increase of the enjoyment at physical exercise after 16 | — |
Countries
Brazil
Contacts
Public ContactRodrigo Browne
Universidade Federal do Rio Grande do Norte - UFRN
Outcome results
None listed