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Facilitation of neurofunctional training with tDCS and rTMS in children with ASD

Facilitation of Neurofunctional Training with tDCS and rTMS on the left dorsolateral prefrontal cortex in children with Autism Spectrum Disorder: a randomized, placebo-controlled, double-blind clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-9xjt5fp
Enrollment
Unknown
Registered
2024-12-18
Start date
2024-12-03
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autism Spectrum Disorder

Interventions

Sponsors

Associação Educativa Evangélica
Lead Sponsor
Clinica de Neuroreabilitação Infantil Follow Kids
Collaborator

Eligibility

Age
3 Years to 8 Years

Inclusion criteria

Inclusion criteria: Diagnosis of autism spectrum disorder confirmed through clinical examination; have a standardized neurobehavioral assessment that confirms and categorizes the severity of autism spectrum disorder; children levels I, II and III according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-V); age between three and eight years of age; children who demonstrate sufficient response to understand simple verbal commands; no medication changes at least six months before the start of the study and during its execution; statement of informed consent signed by a legal guardian and statement of informed assent signed by the participant

Exclusion criteria

Exclusion criteria: Children that having been submitted to surgical procedures or neurolytic block in the 12 months prior to the onset of the training sessions; orthopedic deformities with indication for surgery; epilepsy; metal implants in skull or hearing aids; intellectual disorder that would limit the execution of the intellectual activities proposed in the study

Design outcomes

Primary

MeasureTime frame
It is expected to find an increase in participation assessed by the Participation and Environment Measure for Children and Youth, demonstrated by a 5% increase in scores after the interventions. Data collected one week before the intervention and one and four weeks after the intervention;It is expected to find an increase in functional performance with increased independence in carrying out daily activities, demonstrated by an increase of 5 points in the Pediatric Evaluation of Disability Inventor after the interventions. Data collected one week before the intervention and one and four weeks after the intervention

Secondary

MeasureTime frame
It is expected to find a reduction in the severity of symptoms associated with the disorder, assessed by the Social Responsiveness Scale, with a 3% reduction in the score after the interventions.. Data collected one week before the intervention and one and four weeks after the intervention;Characteristics of autistic behavior evaluated by the Childhood Autism Rating Scale which is an observation scale that will be applied with the person responsible for the participant. The scale will be applied one week before and four and eight weeks after the end of the intervention. It is expected to find a reduction in the severity of autistic symptoms observed by those responsible for the child after the interventions

Contacts

Public ContactClaudia Oliveira

Universidade Evangélica de Goiás

csantos.neuro@gmail.com+55 (11) 99171-6844

Outcome results

None listed

Source: REBEC (via WHO ICTRP)