Diseases of the circulatory system, Endothelium vascular
Conditions
Interventions
Control group: 10 patients sclerotherapy with monoethanolamine oleate diluted in distilled water in the ratio of 1:4 in concentration of 1.25%. Experimental group 1: 09 patients: sclerotherapy with et
Drug
Sponsors
Faculdade de Odontologia da Universidade Federal de Minas Gerais
Faculdade de Odontologia da Universidade Federal de Minas Gerais
Eligibility
Age
10 Years to 86 Years
Inclusion criteria
Inclusion criteria: Patients with oral vascular anomalies less than 20 mm;diagnosis of based on the Mulliken and Glowacki (1982; indications for treatment of these lesions included pain; growth; swelling; pressure or esthetics.
Exclusion criteria
Exclusion criteria: oral vascular anomalies larger than 20mm Lesions that do not have the clinical diagnosis of vascular anamolias. Patients with a history of allergy to the drugs used.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome: Efficacy of monoethanolamine oleate in the clinical cure of vascular anomaly, evaluated by lesion size, in mm, number of sessions and final volume of drug used.;All 3 concentrations of monoethanolamine oleate showed 100% clinical cure of the lesion, observed within a period of 12 months after the last application. Regarding the size of the lesions, there was no statistical difference between the groups, these ranged from 3-20 mm in the 5% and 2.5% concentration groups and 5-20 mm in the 1.25% group. The number of sessions of the 5% concentration group ranged from 1 to 2 sessions and was statistically different (p = 0.03 with the Kruskal-Wallis test) from the other groups (for the 1.25% group the number of sessions ranged from 1 to 4, and for the 2.5% concentration group ranged from 1 to 5 sessions). As for the final volume of monoethanolamine oleate, there was also a statistical difference (p<0.001, Kruskal-Wallis test) between the groups. In the 5% concentration group, 0.1 to 0.4 mL of monoethanolamine oleate was used, whereas for the 1.25% group it ranged from 1 to 4 mL, and for the group of 2.25% from 1 to 5 mL. Therefore, the concentration of 5% monoethanolamine oleate was more effective than the other concentrations, because it presented a smaller number of sessions (1 to 2), smaller volume (0.1 to 0.4 mL) to treat anomalies of size 3 to 20 mm. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected | — |
Countries
Brazil
Contacts
Public ContactRicardo Mesquita
Faculdade de Odontologia da Universidade Federal de Minas Gerais
Outcome results
None listed