Preoperative Period
Conditions
Interventions
The proposed methodology consists of a prospective, controlled, randomized, double-blind, comparative clinical trial with two arms. The objective is to compare the effect of oral carbohydrate preload
G07.203.300.456
Sponsors
Universidade Federal do Piauí
Hospital Getúlio Vargas
Eligibility
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Individuals aged between 18 and 90 years; undergoing elective craniotomy for a single intracranial lesion; who signed the informed consent form
Exclusion criteria
Exclusion criteria: Exclusion criteria: patients with cranial trauma; emergency surgery (making it impossible to perform preoperative preparation with the solution); altered level of consciousness prior to surgery; lack of cooperation; pregnancy; presence of factors that delay gastric emptying or comorbidities that could affect postoperative recovery, such as: paralysis; spinal deformity; autoimmune diseases; coronary artery disease; severe infection; diabetes; or other dysfunctions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A reduction in hospitalization time is expected, as verified by analyzing the total hospitalization time in days via electronic medical records, calculated from the date of admission to the date of hospital discharge.;An improvement in the quality of surgical recovery is expected, assessed by the QoR-15 (Quality of Recovery) questionnaire, where 15 items are evaluated, with the highest value indicating better surgical recovery. | — |
Secondary
| Measure | Time frame |
|---|---|
| An improvement in insulin sensitivity is expected, assessed through the HOMA - IR index (assessed by the relationship between fasting blood glucose and insulin) and capillary blood glucose levels via the On Call Plus II device strip.;An improvement in parameters related to hunger, thirst, pain, nausea and vomiting is expected through the visual analogue scale (VAS) for each of the parameters specifically with values ??from 0 to 10.;An improvement in postoperative muscle strength parameters is expected, assessed using a Fitmetria digital hand dynamometer.;An improvement in the inflammatory response parameters related to surgical trauma is expected, assessed through ultrasensitive C-reactive protein (CRP) measured by nephelometry and turbidimetry.;An improvement in respiratory function parameters is expected, assessed using a “peak flow” device (G-Tech brand device). | — |
Countries
Brazil
Contacts
Public ContactAdriano Oliveira
Universidade Federal do Piauí
Outcome results
None listed