Chronic Obstructive Pulmonary Disease (COPD)
Conditions
Interventions
This was a two-arm randomized clinical trial. Selection bias control was ensured from simple random assignment, in which the list of patients was enumerated to mask the person outside the research who
Sponsors
Universidad Autónoma de Manizales
Alcaldía de Manizales
Eligibility
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: Residents of Manizales, Colombia; aged over 50 years; diagnosis of Chronic obstructive pulmonary disease (COPD) (GOLD I-IV) confirmed by spirometry; evidence of a Forced Expiratory Volume in the first second (FEV1) / Forced Vital Capacity (FVC) ratio less than 70
Exclusion criteria
Exclusion criteria: Diagnosis of known respiratory disorders other than Chronic Obstructive Pulmonary Disease (COPD); history of significant inflammatory disease; malignancy; coronary disease; carrier of osteosynthetic material; partial or total limb amputation; neuromuscular, orthopedic and/or medical disease that impedes or physical exercise; CPOD exacerbation in the four weeks prior to inclusion; recent surgery and participation in pulmonary rehabilitation programs or physical exercises in the last year
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected effect 1. An improvement in muscle function in COPD patients was expected to be found with an increase in meters walked, verified from the 6-minute walk test, based on the minimal clinically significant difference of at least least 25 meters comparing the initial assessment and at 12 weeks of follow-up;Effect found 1. An improvement in muscle function and a statistically significant difference (p=0.004) were observed when comparing the differences after the intervention between the experimental and control groups in the 6-minute walk. In addition, an average difference of 52 meters was achieved, when evaluating the 6-minute walk, between the pre- and post-intervention periods;Expected effect 2. It was expected to find an improvement in muscle function in COPD patients with a decrease in the time spent, verified with the gait speed test, based on the minimum clinically significant difference of at least 0.1 m/sec comparing the initial assessment and at 12 weeks of follow-up;Effect found 2. An improvement in muscle function was observed, reflected in the decrease in the time spent in the gait speed test when comparing the differences after the intervention between the experimental and control groups, obtaining an improvement of 0.2 m/sec | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected effect 3. It was expected to find an improvement in the symptoms of patients with COPD, verified from the application of the COPD Assessment Tests (CAT) questionnaire, based on the minimum clinically significant difference of at least 2 units after the application of a 12-week physical training intervention in patients with COPD;Effect found 3. An improvement in the symptoms of COPD patients was observed, evidenced by a statistically significant difference (p=0.004) when comparing the differences after the intervention between the experimental and control groups in the COPD Assessment Tests (CAT) questionnaire. , obtaining an improvement of 7 units in said questionnaire;Expected effect 4. It was expected to find an improvement in the quality of life of patients with COPD, verified by applying the St. George quality of life questionnaire, based on the minimum clinically significant difference of at least 4 units after the application of a 12-week physical training intervention in patients with COPD;Effect found 4. An improvement in the quality of life of patients with COPD was observed, evidenced in the statistically significant difference in each of the dimensions of this questionnaire (p=0.0001) when comparing the differences after the intervention between the experimental and control group in the St. George questionnaire, obtaining an improvement of 18 units | — |
Countries
Colombia
Contacts
Public ContactMaria Pineda Zuluaga
Universidad Autónoma de Manizales
Outcome results
None listed