Alveolar Bone Loss
Conditions
Interventions
Sponsors
Federico Henriquez y Carvajal University
Eligibility
Age
21 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients with a small bone defect in the upper jaw that must be regenerated before dental implants are placed; ASA I or II patients; patients over 21 years of age; patients with good oral hygiene
Exclusion criteria
Exclusion criteria: Systemic alterations; infection in the area of regeneration; patients with chemotherapy or radiotherapy treatment; patients who smoke; patients with systemic diseases; pregnant or breastfeeding women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected primary outcome 1- Bone formation. In the bone volume comparison between the initial CBCT (before surgery) and the final one (4 months after scaffolding). Positive values are expected both in % and in millimetres of mineralised tissue. ;Expected primary outcome 2- Evaluation of the bone neoformation Biopsies of the regenerated area will be taken (4 months after the placement of the scaffolding) and then a histomorphometric examination will be performed to assess the presence or not of neoformed bone tissue. It is expected that the presence of neoformed tissue will be around 15%-30%. | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected secondary outcome 1- Neoformed bone ensures quality for the placement of dental implants. The primary stability of dental implants (placed 4 months after scaffolding) will be measured by means of resonance frequency analysis. It will be measured on the day of the surgery for the placement of the implants. Any ISQ value above 60 will be given as a positive result.;Expected secondary outcome 2-Bone formation. In the bone volume comparison between 4 months CBCT and 8 months CBCT. It is expected that the placement of the implants at 4 months will not affect the bone formation. Positive values are expected both in % and in millimetres of mineralised tissue. ;Secondary expected outcome 3- The neoformed bone ensures the quality for the survival of the dental implants. To evaluate the secondary stability of dental implants by means of resonance frequency analysis. It will be measured 4 months after the placement of the implants which is 8 months after the placement of the scaffolding. Any ISQ value above 60 will be given as a positive result. | — |
Countries
Dominican Republic
Contacts
Public ContactAna Suarez
Universidad Europea de Madrid
Outcome results
None listed