Skip to content

Recovery of the diaphragm muscle after removal of mechanical ventilation support

Diaphragmatic rehabilitation after weaning from mechanical ventilation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-9w6wd89
Enrollment
Unknown
Registered
2025-04-21
Start date
2025-02-02
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Artificial respiration

Interventions

This is a randomized, controlled, two-arm clinical trial. Patients who have been on mechanical ventilation for more than 48 hours, who are eligible for weaning from mechanical ventilation and who have

Sponsors

Hospital Geral Roberto Santos
Lead Sponsor
Hospital Geral Roberto Santos
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adult patients; of both sexes; aged 18 years or older; with hypoxemic respiratory failure treated by prolonged invasive mechanical ventilation for more than 48 hours and who have been extubated after a successful spontaneous breathing trial; evaluated by lung ultrasound with a pulmonary ultrasound score of less than 14 points and diaphragmatic dysfunction characterized by a diaphragmatic thickness fraction = 36% diagnosed by diaphragmatic ultrasound

Exclusion criteria

Exclusion criteria: Patients with Chronic Obstructive Pulmonary Disease (COPD); Patients in palliative care; Patients with Respiratory failure secondary to neuromuscular syndromes; Patients without an ultrasound window will be excluded from the study

Design outcomes

Primary

MeasureTime frame
Participants in the experimental group are expected to have a lower rate of return to mechanical ventilation than participants in the control group.

Secondary

MeasureTime frame
No secondary outcomes are expected

Countries

Brazil

Contacts

Public ContactEmídio Jorge Lima

Hospital Geral Roberto Santos

emidio.lima@gmail.com+55 71 9 88286059

Outcome results

None listed

Source: REBEC (via WHO ICTRP)