Diabetic Foot
Conditions
Interventions
Participants will be followed up for 12 weeks, attending the outpatient consultation once a week, where biological material will be collected at the first consultation (T0), at the fifth consultation
E07.632.490
Sponsors
Faculdade de Enfermagem - Universidade Estadual de Campinas
Universidade Federal Fluminense
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Participants with diabetes mellitus; both genders; aged 18 or over; foot wound
Exclusion criteria
Exclusion criteria: Lupus; pyoderma gangrenosum; Steve Johnson Syndrome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in wound area size from initiation of treatment to end of follow-up period, 12 weeks. The difference in the area of the wound will be evaluated through the weekly photographs, the photos will be inserted in the ImageJ software that calculates the area in square centimeters. | — |
Secondary
| Measure | Time frame |
|---|---|
| Wound area reduction will be measured in square centimeters (cm2), length x width of the area will be measured in cm2 and area change calculated in percentage (%). Wound closure will be expressed in %, calculated by the following mathematical formula, called the ulcer contraction index (ICU): ICU= Initial wound area- (Daily area)(Initial area) x 100% ;Analysis of the expression of inflammatory cytokines using the polymerase chain reaction (PCR) technique and enzyme-linked immunosorbent assay (ELISA);The appearance of tissue quality in the wound bed (granulation tissue), decrease in exudate, appearance and contraction of edges will be assessed using the Bates-Jansen Wound Assessment Tool. | — |
Countries
Brazil
Contacts
Public ContactBeatriz Barbieri
Faculdade de Enfermagem - Universidade Estadual de Campinas
Outcome results
None listed