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Ability of a Test that simulates spontaneous breathing predict successful extubation of Premature Infants: comparison between two protocols

Spontaneous Breathing Test as a predictor of successful extubation in Extremely Preterms Infants: comparison between two protocols

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-9vdnz3
Enrollment
Unknown
Registered
2018-10-18
Start date
2018-05-02
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory distress syndrome of newborn

Interventions

Infants will be included in the study as soon as they meet the extubation criteria, which are considered the "gold standard" to define the ideal time for extubation and are defined by the Neonatal Int
Other

Sponsors

Centro Universitário CESMAC
Lead Sponsor
Universidade Federal de Sergipe
Collaborator
Universidade Estadual de Ciências da Saúde de Alagoas
Collaborator

Eligibility

Age
24 Weeks to 33 Weeks

Inclusion criteria

Inclusion criteria: Preterm infants; both sexes; birth weight less than 1500g; Early Respiratory Distress Syndrome diagnostic; on invasive mechanical ventilation for more than 24 hours.

Exclusion criteria

Exclusion criteria: Presence of cardiac malformation, neurological dysfunction or genetic syndrome; occurrence of non-scheduled extubation or death before extubation.

Design outcomes

Primary

MeasureTime frame
72 hour reintubation rate Infant reintubation rate at 7 days, assessed by the number of infants who return for invasive mechanical ventilation after being extubated and placed on noninvasive ventilation in each study group, measured between the time of extubation up to 7 days after.

Secondary

MeasureTime frame
Infant reintubation rate at 7 days, assessed by the number of infants who return for invasive mechanical ventilation after being extubated and placed on noninvasive ventilation in each study group, measured between the time of extubation up to 7 days after. ;Infant reintubation rate at 14 days, assessed by the number of infants who return for invasive mechanical ventilation after being extubated and placed on noninvasive ventilation in each study group, measured between the time of extubation up to 14 days after.;Total hospitalization time, measured by the total time in hours the baby stays in the hospital, from birth to discharge, considering the various sectors of the maternity unit.;Mortality rate, measured by number of deaths among infants included in the study;Incidence of pulmonary bronchodysplasia, measured by the number of babies included in the study who present the diagnosis of pulmonary bronchodysplasia until hospital discharge, evaluated by the registry of the disease in medical records

Countries

Brazil

Contacts

Public ContactRaphaela Farias Teixeira

Centro Universitário CESMAC

ftraphaelafarias@hotmail.com+55-082-999803853

Outcome results

None listed

Source: REBEC (via WHO ICTRP)