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Effect of the topical application of an anti-inflammatory in the reduction of dental sensitivity after office dental bleaching

Effect of Topical Application of Arginine-Associated Ibuprofen on Reduction of Dental Sensitivity after Dental Bleaching in the Office

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-9v2xz6
Enrollment
Unknown
Registered
2019-01-23
Start date
2019-02-25
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dentin Sensitivity, Dental Bleaching

Interventions

It will be a mouth-divided study. Experimental group: For the 60 volunteers, the desensitizer for topical use containing ibuprofen and arginine will be applied to the vestibular surface of the teeth o
E06.420.750

Sponsors

UEPG - Universidade Estadual de Ponta Grossa
Lead Sponsor
UEPG - Universidade Estadual de Ponta Grossa
Collaborator

Eligibility

Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Healthy volunteers; Both genders; Age between 18 and 40 years, with upper and lower anterior teeth with vitality; Adequate oral hygiene; With central incisors that should be A2 or darker in color according to the Vita scale (VITA classical, VITA Zahnfabrik, Bad Säckingen, Germany)

Exclusion criteria

Exclusion criteria: Voluntary smokers; Pregnant and lactating women; Patients with teeth showing staining caused by tetracycline; Fluorosis; Hyperplasia; endodontic treatment; Presence of restorations in the eight upper and lower anterior teeth; Previous dental sensitivity; Parafunctional habits; Cervical lesions (abrasion, erosion and abfraction), periodontal disease.

Design outcomes

Primary

MeasureTime frame
Expected outcome: The color difference between the initial condition and 1 month after bleaching will be assessed using the Vita Classical and Vita Bleachedguide color scales and also with the Vita Easyshade spectrophotometer. The data will be presented in the form of means and standard deviations. No interference is expected from the application of the gel containing ibuprofen and arginine prior to bleaching in the results of the bleaching treatment in any of the evaluated groups—

Secondary

MeasureTime frame
Expected outcome: The intensity of tooth sensitivity will be assessed using the numeric 5-point scale (NRS 0-4) and the visual analogue scale (VAS 0-10) and will be presented as means and standard deviations in different periods (during dental bleaching, up to 1 h, 1 h to 24 h and 24 h to 48 h post-bleaching)—

Countries

Brazil

Contacts

Public ContactOsnara Mongruel Gomes

UEPG - Universidade Estadual de Ponta Grossa

osnaramgomes@uol.com.br+55-42-3220-3740

Outcome results

None listed

Source: REBEC (via WHO ICTRP)