Skip to content

Research of the effect x costs in the treatment of the dwelling area of coxa skin enlargement in burned patients. Comparison between dressing with ibuprofen, foam with silicone and cellulose fiber mesh

Clinical cost-effectiveness test for treatment of the different area of partial thickness skin enlargement in burned patients. Comparison between polyurethane foam with ibupphrine, polyurethane foam with silicone and fiber mesh of salinized cellulose

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-9tvrzb
Enrollment
Unknown
Registered
2018-12-02
Start date
2018-11-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain in skin graft donor area Re-epithelialization in skin graft donor area

Interventions

Group a - accomplishment in 30 patients, dressing in partial donor area of partial skin graft with polyurethane foam with ibuprofen, maintained until wound healing Group b - accomplishment in 30 patie
Drug
Device
Procedure/surgery

Sponsors

Unidade de Queimados da Unidade de Emergência do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo-UQHCFMRP-USP
Lead Sponsor
Unidade de Queimados da Unidade de Emergência do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo-UQHCFMRP-USP
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Age greater than 10 years; patients submitted to partial skin grafting of 0.2 mm, removed from the thigh region with Aesculap® brand of electric dermatome.

Exclusion criteria

Exclusion criteria: known allergy to the components of the dressing; cognitive disorder; sensorial losses in donor areas; sedated patients or children under 10 years or with little understanding of the objectives of the studies and communication; need to modify the type of bandage during the study period; use of another model of an electric dermatome device for removal of skin; removal of skin in a thickness other than 0.2 mm; patients previously submitted to local anesthetic blocks

Design outcomes

Primary

MeasureTime frame
Pain evaluation Data on pain will be obtained by means of rating scales use of validated pain for use in adult patients (EVA) made by professional assistant of the patient within 48 hours, in the seventh and tenth day, and the patient should not have been submitted to local anesthetic blockades. At each questioning of pain, the objectives and functioning of the pain scale will be explained.

Secondary

MeasureTime frame
Evaluation of reepithelialization and infection The partial thickness skin graft donor area will be considered completely re-epithelialized (restored) when about 95% of the wound is healed. This analysis will be done by means of photographs and clinical evaluation by an experienced UQ professional. The re-epithelialization area can be measured by use of Image-J software. The appearance of the donor area will be analyzed on the first, seventh and tenth postoperative days, with signs of infection (border hyperemia, increase or change in local secretion pattern, presence of odor suggestive of infection). After the seventh day, an emollient (essential fatty acids) will be applied to facilitate the removal of the cellulose fiber mesh.;Evaluation of the exchange of dressing The patients included in study group A and B will have a dressing change performed every 7 days, according to the manufacturer's instructions. Patients included in the C-control study group will not have the same dressing change sequence as groups A and B. The justification for this is that the rayon dressing soaked in saline after an average of 6 hours is dry and firmly adhered to the bed, making it impossible to exchange, since it would cause more pain, local bleeding and damage to the healing process of the donor area of the participants.

Countries

Brazil

Contacts

Public ContactHenrique Coraspe Gonçalves

Unidade de Queimados da Unidade de Emergência do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo-UQHCFMRP-USP

henrique_coraspe@hotmail.com551636021140

Outcome results

None listed

Source: REBEC (via WHO ICTRP)