Recurrent Depressive Disorder, Depressive Episode
Conditions
Interventions
This is a single-blind randomized clinical trial composed of three experimental groups: a high-volume group (HV), a low-volume group (LV), and a control group (CG), with 30 participants in each group
E02.760.169.063.500.387.875
Sponsors
Univerdade Estadual Paulista Júlio de Mesquita Filho
Univerdade Estadual Paulista Júlio de Mesquita Filho
Eligibility
Age
18 Years to 59 Years
Inclusion criteria
Inclusion criteria: Men or women aged 18 to 59; Diagnosis of major depressive disorder (single or recurrent episodes) by a psychiatrist; No psychiatric comorbidities such as schizophrenia, bipolar disorder, or substance abuse disorder; For women, not being pregnant or lactating; No participation in regular resistance training in the past six months; No cardiovascular or musculoskeletal contraindications that may limit participation in the exercise program
Exclusion criteria
Exclusion criteria: Missing six or more exercise sessions during the intervention; Missing three consecutive sessions; Failing to complete the scheduled assessments during the intervention
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To verify the influence of eight weeks of resistance training (RT) volume and a six-month follow-up period after training cessation on the reduction of depressive symptoms in patients with Major Depressive Disorder (MDD). | — |
Secondary
| Measure | Time frame |
|---|---|
| To identify the most effective RT volume to reduce depressive symptoms in MDD patients ;To compare the effect of eight weeks of high and low RT volume on exercise program self-efficacy in MDD patients;To compare the effect of eight weeks of high and low RT volume on serum biomarkers in MDD patients;To verify the relationship between changes in serum biomarkers and changes in depressive symptoms induced by eight weeks of high and low RT volume in MDD patients;To examine depressive symptoms scores during a six-month follow-up after training cessation in MDD patients | — |
Countries
Brazil
Contacts
Public ContactJessenia Marise Campos
Univerdade Estadual Paulista Júlio de Mesquita Filho
Outcome results
None listed