Effect of Transcranial Electrical Stimulation and Intensive Physical Therapy in Cerebral Palsy

Effect of Transcranial Direct Current Stimulation and Intensive Physical Therapy in Spastic Diparetic Cerebral Palsy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

REBEC

Registry ID

RBR-9syxzh3

Enrollment

Registered

2026-03-27

Start date

2025-01-10

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spastic Diplegic Cerebral Palsy Cerebral Palsy

Interventions

This is a case report. Subject: a 17-year-old male adolescent with spastic diparetic cerebral palsy, classified at level II of the Gross Motor Function Classification (GMFCS). The participant underwen

strengthening exercises for the abdominal muscles, gluteus maximus, gluteus medius, quadriceps, and triceps surae, with progressive overload, starting with 3 sets of 10 repetitions and increasing over

and functional exercises such as squats, stair climbing and descending, and treadmill walking. The Transcranial Direct Current Stimulation protocol involved two settings and was applied for a period o

Eligibility

Sex/Gender

Male

Age

10 Years to 18 Years

Inclusion criteria

Inclusion criteria: Adolescent diagnosed with spastic diparetic cerebral palsy; ability to understand and follow simple instructions; availability to participate in all intervention and assessment sessions; absence of medical contraindications for undergoing transcranial direct current stimulation.

Exclusion criteria

Exclusion criteria: Presence of other neurological conditions that may affect the evaluation of results; presence of metallic implants or electrical devices in the skull that may interfere with the use of tDCS; history of uncontrolled seizures.

Design outcomes

Primary

Measure	Time frame
Expected outcome: It is expected to find an increase in gait speed, improvement in functional abilities, and improvement in time in the upright position, as well as to contribute to the understanding of the effects of combined therapies on the control of spastic diparetic cerebral palsy, providing knowledge for clinical practice and the development of a more effective approach.;Outcome found: A 12% improvement in gross motor function was observed, assessed by the GMFM-66, with an increase in total score and better performance in dimension E (“walking, running, and jumping”); improvement in postural control and functional mobility, with a 32% reduction in total TUG time, 90% reduction in ellipse area, and increased stability and gait speed; increase in distance covered in the 6-minute walk test from 245 m to 468 m, indicating improved physical endurance and functional capacity.	—

Measure

Time frame

Expected outcome: It is expected to find an increase in gait speed, improvement in functional abilities, and improvement in time in the upright position, as well as to contribute to the understanding of the effects of combined therapies on the control of spastic diparetic cerebral palsy, providing knowledge for clinical practice and the development of a more effective approach.;Outcome found: A 12% improvement in gross motor function was observed, assessed by the GMFM-66, with an increase in total score and better performance in dimension E (“walking, running, and jumping”); improvement in postural control and functional mobility, with a 32% reduction in total TUG time, 90% reduction in ellipse area, and increased stability and gait speed; increase in distance covered in the 6-minute walk test from 245 m to 468 m, indicating improved physical endurance and functional capacity.

—

Secondary

Measure	Time frame
No secondary outcomes are expected	—

Countries

Contacts

Public ContactThais Contenças

Universidade Federal de São Paulo

thais.contencas@unifesp.br+55 (11) 3385-4255

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Apr 4, 2026