Osteoradionecrosis
Conditions
Interventions
This is a prospective, randomized, controlled study that will evaluate the efficacy of aPDT (antimicrobian photodynamic therapy). in patients with osteonecrosis of the jaw bones treated at the stomato
60 years and = 60 years), type of osteonecrosis (associated with medication or radiotherapy) and classification of osteonecrosis (initial: grade 1 and 2, and advanced: grade 3). The MRONJ (medication-
Sponsors
Fundação Antônio Prudente
Fundação Antônio Prudente
Eligibility
Inclusion criteria
Inclusion criteria: any age; male or female; osteoradionecrosis; medication-related osteonecrosis of the jaws; who signed the Informed Consent Form.
Exclusion criteria
Exclusion criteria: patients who did not have the clinical conditions to undergo antimicrobian photodynamic therapy (aPDT); who did not agree with this therapeutic modality; stage 0
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected that the necrotic area will be completely epithelialized after spontaneous bone sequestration.The response to treatment was evaluated at the last consultation, according to Lopes et al. in 3 levels: Complete healing: the treated area was completely covered by the oral mucosa, with no bone exposure or suppuration. Partial healing: a reduction in exposed bone and symptoms, mainly pain, was found. No healing: the treatment was not effective, and the clinical aspects and symptoms remained similar to the period before treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcomes are expected | — |
Countries
BR
Contacts
Public ContactMayara Souza
Fundação Antônio Prudente
Outcome results
None listed