Cognitive Dysfunction
Conditions
Interventions
All participants will receive the intervention. The training protocol will consist of five sets of 1 minute of static squatting (isometric knee flexion at 20 degrees), on a synchronous vibrating platf
Sponsors
Universidade Federal dos Vales do Jequitinhonha e Mucuri
CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Eligibility
Age
80 Years to No maximum
Inclusion criteria
Inclusion criteria: Age 80 years or older; present a clinical picture of Mild Cognitive Impairment, according to the Montreal Cognitive Assessment (MoCA); be considered insufficiently active based on the result of the Active Australia Questionnaire (AAQ); not being on immunosuppressive and/or anti-inflammatory medication, and report any medications in use.
Exclusion criteria
Exclusion criteria: Participants will be excluded if they have epilepsy, gallstones, kidney stones, stroke/apoplexy, decompensated heart, metabolic and chronic inflammatory diseases, those who have an implant, bypass, or stent, those who have a hearing disorder and/or severe visual impairment and refusal to sign the informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome: Feasibility Study feasibility will involve analysis of recruitment, intervention, acceptability, safety, measurement, and timing. Recruitment feasibility will be determined by calculating the proportion of eligible and consenting participants from the very elderly population with mild cognitive impairment admitted to health centers in the local community. This will be determined through records: the number of very old people with mild cognitive impairment in local community health centers selected for eligibility; the number of eligible; and the number of subscribers. The feasibility of the intervention will be determined by examining the participant's adherence to the intervention (support in positioning to receive whole body vibratory stimulation, feedback and progression throughout the session) as well as the average time spent during the session. Participant acceptability to the intervention will be measured through a survey following the intervention phase. Participants will rate four statements about the intervention on a five-point acceptability scale, from strongly disagree to strongly agree. If necessary, an interpreter or speech therapist will help the participant complete the survey. Safety will be measured by recording events such as fatigue, muscle soreness, non-injury falls, injurious falls and death. The feasibility of the measurement protocol will be determined by the ability to measure clinical outcomes across all participants. | — |
Secondary
| Measure | Time frame |
|---|---|
| Physical function: The assessment of physical functions will include the measurement of functional performance, global muscle strength, and mobility through the application of three functional measures: Short Physical Performance Battery (SPPB), handgrip strength (HGS), and dual-task, respectively. Short Physical Performance Battery (SPPB) The SPPB is a functional performance test that assesses the function of the lower limbs (LL) considering balance, gait, strength and endurance, and is used to screen elderly people at risk of developing future disabilities. The instrument is composed of tests of: standing static balance; gait speed at usual pace; LL muscle strength estimated by the test of sitting down and getting up from a chair without the aid of the arms five times. For each test, the performance obtained is scored from 0 (worst performance) to 4 (best performance) and the final score is calculated, which can be a maximum of 12 points. Thus, those individuals who obtain a score from 0 to 3 – will have poor performance or have some type of disability; grades 4 to 6 – indicate low performance; grades from 7 to 9 demonstrate moderate performance and from 10 to 12 denote good performance. Handgrip Strength (HGS) HGS measurements are widely used as an indicator of general muscle strength, especially among the elderly. HGS will be measured using a Jamar® dynamometer (Asimow Engineering Co.), respecting the protocol recommended by the American Association of Hand Therapists. For this, the subject should be in a sitting position, with feet flat on the floor, shoulder adducted and in neutral rotation and elbow at 90º. The forearm and wrist in a neutral position, with a slight wrist extension allowed (up to 30º). FPM will be expressed in kilograms-force (KgF), through an isometric contraction applied on its handles. Three measurements will be taken and the FPM will result from the average of the results. An interval of one minute will be given between each of the m | — |
Countries
Brazil
Contacts
Public ContactArthur Arrieiro
Universidade Federal dos Vales do Jequitinhonha e Mucuri
Outcome results
None listed