Sleep Apnea, Obstructive
Conditions
Interventions
This is a two-arm randomized crossover clinical study. Experimental group 1: 20 overweight individuals diagnosed with obstructive sleep apnea will reduce their eating time to 8 hours and maintain the
Sponsors
Universidade Federal de Lavras
Universidade Federal de Lavras
Eligibility
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Adult individuals aged between 18 and 60 years; with a Body Mass Index (BMI) between 25 and 40 Kg/m²; diagnosed with sleep apnea obstructive by polysomnography and/or medical diagnosis made in the last 6 months; whether or not they are being treated with oxygen therapy such as Continuous Positive Airway Pressure (CPAP) or Bilevel Positive Airway Pressure (BiPAP); of both sexes; with a feeding window between 11 and 14 hours
Exclusion criteria
Exclusion criteria: Individuals who have a serious illness such as cancer, liver or kidney disease; pregnant women or those with children up to two years old; institutionalised elderly people; individuals who are engaged in some kind of weight loss treatment or nutritional monitoring; those taking medication that interferes with metabolic rate (appetite suppressants, thyroid hormones); people who have a physical or intellectual disability proven by a medical diagnosis; people who are unable to take part in the proposed assessments; people who refuse to take part in the proposed assessments or interventions; people who have other sleep disorders such as insomnia, restless legs syndrome, narcolepsy; shift or night workers; participants who do not adhere to the proposed treatment; people who do not complete the proposed assessments
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is hoped to find a reduction in the average oxygen desaturation index (ODI) and other sleep parameters assessed using a digital finger oximeter (type IV polysomnography) | — |
Secondary
| Measure | Time frame |
|---|---|
| We expect to find changes in the composition and abundance of the oral microbiota, mainly related to the Firmicutes and Bacteroidetes phyla, obtained through cytological mouth brushing;The reduction in body fat mass and maintenance of muscle mass obtained through electrical bioimpedance are expected;Improvements are expected in metabolic markers such as fasting blood glucose, total cholesterol and fractions, glycated hemoglobin (HbG) and the inflammatory marker C-reactive protein (CRP) | — |
Countries
Brazil
Contacts
Public ContactCamila Maria de Melo
Universidade Federal de Lavras
Outcome results
None listed