Diseases of the Nervous System, Mild Cognitive Impairment.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Healthy volunteers and with mild cognitive impairment, both of genders; aged between 65 and 75 years; literate (minimum education of four years of formal education), present good understanding, able to identify colors; accomplish all test items Short Physical Performance Battery (SPPB). To define the diagnostic groups were included: Volunteers with a clinical diagnosis of mild cognitive impairment; predominantly mnemonic function (amnestic Mild Cognitive Impairment of type); without impairment of functional capacity; seen at the Hospital das Clinicas da USP. Cognitively healthy volunteers: no evidence of cognitive or functional second clinical and neuropsychological impairment.
Exclusion criteria
Exclusion criteria: Volunteers with metal devices in the body and pacemakers; history of dementia or depression; cognitive changes secondary to other degenerative diseases such as Parkinson's disease and stroke; presence of other neurological diseases liable to interfere in cognition or mobility (Parkinson's disease, Multiple Sclerosis, Huntington's Disease, epilepsy, head injury) and sensorimotor and / or vestibular sequelae; severe clinical disease and adequate control off as hypertension, diabetes mellitus, chronic obstructive pulmonary disease, heart failure, kidney failure, liver failure; visual and auditory impairment uncorrected; presence of any orthopedic condition or severe rheumatologic or without control of symptoms as reporting pain, discomfort or recent surgery of the lower limbs, and other difficulties that could hinder the accomplishment of assessments; complaints of dizziness, vertigo, or history of frequent falls; significant decrease in performance in daily activities; using devices for walking (such as a cane, crutch, walker or wheelchair); refusal to signing the informed consent form (ICF) or participate in the evaluations proposed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected to find a decrease in displacement of the standing posture in elderly people with mild cognitive impairment. To do this, an evaluation of static postural balance in a device that uses a electromagnetic sensor system model / brand Polhemus® / Patriot is performed. In this evaluation, the volunteer is asked to stand up, not moving during the evaluation time. Will be measured displacement which the body does to keep in balance in this position. The analysis of the primary endpoint will be a comparison of balance test between healthy volunteers and mild cognitive impairment. For this purpose is used a comparison between the analysis made by the middle displacement achieved by each group of volunteers.;The reduction of static body balance was observed in volunteers with mild cognitive impairment when compared to the healthy group through the larger displacement of volunteers with mild cognitive impairment in all sensory conditions (eyes open, eyes closed and on a soft foam). | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected to find differences between muscle strength, gait time, body sensitivity, cognitive performance and cost of dual task between these two groups. For this, will be assessed muscle strength of the lower limbs, gait and sensitivity by applying the test battery Short Physical Performance Battery (SPPB), cognitive performance, with the Mini Mental State Examination and cost of the dual task in balancing test postural generated by the cost of the dual task on simple task. Expected to find better average performance in the healthy group.;Found less muscle strength in the lower limbs and shorter time to march the execution, with the lowest total score in the Short Physical Performance Battery Battery Tests (SPPB), lower cognitive scores on the Mini Mental State Examination test the volunteer group with mild cognitive impairment when compared with the group of healthy volunteers. Assessment of postural balance through body movement showed higher body displacement when sensory information was taken as vision and proprioception of the feet and higher cost of the dual task, given in percent, on body balance in the group of volunteers with mild cognitive impairment. | — |
Countries
Brazil
Contacts
Faculdade de Medicina de Ribeirão Preto - FMRP-USP