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Curcumin and women’s health: investigating its effects in women with overweight and polycystic ovary syndrome

Effects of curcumin supplementation on metabolic parameters in overweight and obese women with polycystic ovary syndrome: a randomized double-blind placebo-controlled clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-9p8jnf9
Enrollment
Unknown
Registered
2025-12-02
Start date
2023-03-02
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic Ovary Syndrome

Interventions

This is a randomized clinical trial with 2 arms, double blind and placebo controlled, the experimental group consisted of 14 women with polycystic ovary syndrome and overweight who received curcumin c

Sponsors

Centro de Saúde Escola da Faculdade de Medicina de Ribeirão Preto - USP
Lead Sponsor
Centro de Saúde Escola da Faculdade de Medicina de Ribeirão Preto - USP
Collaborator

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: The sample consisted of women diagnosed with polycystic ovary syndrome who met the inclusion criteria which are women aged between 18 and 40 years; women classified as overweight and obesity grade I and II with body mass index greater than or equal to 25 kilograms per square meter and less than or equal to 39.9 kilograms per square meter

Exclusion criteria

Exclusion criteria: Participants were excluded from the study if they reported an allergy to curcumin or its derivatives, or presented with any of the following conditions pregnancy or breastfeeding period; late-onset congenital adrenal hyperplasia; androgen-secreting tumors; thyroid dysfunction; hyperprolactinemia; cushing's syndrome; ovarian insufficiency; hypothalamic amenorrhea; chronic kidney disease

Design outcomes

Primary

MeasureTime frame
It is expected to find a significant improvement in metabolic parameters and antioxidant capacity of overweight women with polycystic ovary syndrome after 12 weeks of curcumin supplementation, compared to the placebo group.

Secondary

MeasureTime frame
No secondary outcomes are expected.

Countries

Brazil

Contacts

Public ContactJúlia Ramos

Faculdade de Medicina de Ribeirão Preto

juliaramos@usp.br55(16)997696178

Outcome results

None listed

Source: REBEC (via WHO ICTRP)