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How physical training is able to improve chest pain in patients without coronary disease

Study of the mechanisms involved in the beneficial effects of aerobic physical training in patients with coronary microvascular dysfunction

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
REBEC
Registry ID
RBR-9p4kst
Enrollment
Unknown
Registered
2019-06-17
Start date
2012-04-02
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Angina Microvascular

Interventions

The patients in supervised training (n=30) undergoing will undergo 3 weekly cardiovascular rehabilitation sessions of aerobic exercise on an exercise treadmill in the fitness room of the HCFMRP - USP
Other
G11.427.410.698.277

Sponsors

Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo
Lead Sponsor
Hospital Das Clinicas da Faculdade de Medicina de Ribeirão Preto - USP
Collaborator

Eligibility

Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with a diagnosis of coronary microvascular angina. Patients of both genders, aged between 18 and 80 years.

Exclusion criteria

Exclusion criteria: Precordial pain whose clinical features suggest non-ischemic origin; Presence of obstructive lesions in coronary arteries that irrigate the ischemic area; Physical limitation to aerobic exercise on treadmill; Contraindication to the practice of moderate intensity aerobic physical activity.

Design outcomes

Primary

MeasureTime frame
Whether physical training would be able to reduce the patient's anginal frame. Evaluated by the quality of life questionnaire. ;Whether physical training would be able to reduce myocardial perfusion defects. Evaluated by myocardial perfusion scintigraphy.

Secondary

MeasureTime frame
Whether physical training would increase the patients' physical capacity. Evaluated by cardiopulmonary test.;Whether the improvement in the anginal condition would be associated with an improvement in the quality of life. Evaluated by the quality of life questionnaire. ;What mechanisms would be involved in improving myocardial perfusion. Evaluated by endothelial function and autonomic control.

Countries

Brazil

Contacts

Public ContactEduardo Elias;Eduardo Elias Carvalho;de Carvalho

Universidade Federal do Triangulo Mineiro;Universidade Federal do Triangulo Mineiro

eduardo.carvalho@uftm.edu.br;eduardo.carvalho@uftm.edu.br34 3700-6812;+55-34-33387177

Outcome results

None listed

Source: REBEC (via WHO ICTRP)