Gingivitis
Conditions
Interventions
As this is an observational investigation, there is no intervention in this study. The objective of this study will be to evaluate the salivary proteomic profile related to obesity and gingivitis in w
with obesity but without gingivitis (ONG = 10)
with normal BMI but with gingivitis (NG = 10)
with normal BMI and no gingivitis (NNG = 10). Saliva samples will be collected and analyzed to investigate proteins associated with obesity and gingivitis. Observational measurements will be: anthropo
Sponsors
Faculdade de Odontologia de Bauru - Universidade de São Paulo
Faculdade de Odontologia de Bauru - Universidade de São Paulo
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Pregnant women in the 3rd trimester of pregnancy; between 18 and 40 years of age; regular follow-up with the obstetrician; and who present adequate cognitive and neuromotor behavior; adequate ability to perform regular oral hygiene
Exclusion criteria
Exclusion criteria: Periodontitis; systemic arterial hypertension diagnosed before or during pregnancy; pre eclampsia; Gestational Diabetes Mellitus; Pre-pregnancy BMI lower than 18.5 kg/m2; Pre-pregnancy BMI between 25–29.99 kg/m2; diagnosed or suspected of being infected with SARS-CoV-2; absolute rest required; any other systemic disease; current use or use during pregnancy of antibiotics or any medication that harm periodontal condition and salivary flow; hyposalivation; consumption of any food or drink one hour or less before saliva collection; one or more cavitated carious lesions; multiple tooth loss; tooth loss prior to pregnancy due to periodontitis; undergoing orthodontic, periodontal or any dental treatment with another dentist; previous surgical periodontal treatment; use of alcohol/tobacco/illegal drugs during pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome. It is expected to find differentially expressed proteins in the saliva of pregnant women with obesity and gingivitis using a mass spectrometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcomes expected | — |
Countries
Brazil
Contacts
Public ContactGerson Foratori Junior
Faculdade de Odontologia de Bauru - Universidade de São Paulo
Outcome results
None listed