Neoplasia, Stomatitis
Conditions
Interventions
Group 1: will consist of 30 patients under exclusive chemotherapy treatment, regardless of the type of cancer (solid or hematological) and anatomical site, which after random draw will integrate the s
mouthwash with chlorhexidine 0.12% oral solution 12 / 12h (presence of at least 1 tooth in mouth)
mouthwash with oral nystatin solution 6 / 6h - 1,000UI
removal, cleaning and storage of appliances and / or dental prostheses).
Subgroup 1b - will consist of 10 patients from group 1 - oral care using the protocol used in the routine of the Service (oral
removal, cleaning and storage of appliances and / or dental prostheses) and topical application of copaiba oil 1 (once) a day, all over the oral mucosa.
Subgroup 1c - will consist of 10 patients from
removal, cleaning and storage of appliances and / or dental prostheses) and to
Drug
E02.594.540
E02.190
Sponsors
Universidade de Pernambuco
Universidade de Pernambuco
Eligibility
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Including individuals of both sexes, aged 18 years or older, diagnosed with solid or hematologic malignancy and under chemotherapy or radiotherapy, the latter in the head and neck region, at the Oncology Center of the Oswaldo Cruz University Hospital, to agree to conduct this study after signing the Informed Consent Form, thus allowing the use, after random draw, of one of the three methods used in this study for prevention and treatment of chemoinduced and radioinduced oral mucositis.
Exclusion criteria
Exclusion criteria: Individuals who do not meet the inclusion criteria; Individuals who meet the inclusion criteria but disagree with the study and / or individuals who initially allow the study and then express their desire to abandon the study will be excluded; Also individuals who abandon the oncological or dental treatment for oral mucositis control during the research period, or who die without being able to complete the analysis of oral condition and mucositis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decrease in the number of severe cases of oral mucositis, verified using the acute toxicity scale proposed by the WHO, based on the finding of a reduction in cases equivalent to grades III and IV of oral mucositis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Adherence of patients, family members and medical staff regarding copaiba oil, verified through the reporting of experiences. | — |
Countries
Brazil
Contacts
Public ContactAurora Vidal
Universidade de Pernambuco
Outcome results
None listed