Skin and connective tissue diseases, Infant, Newborn, Skin, Soaps, Skin Care
Conditions
Interventions
The 204 recruited newborns were randomized into 2 groups, into 2 groups, each one with 102 participants: the group that used mildly acidic infant liquid soap and the liquid soap commonly used in the m
E02.547.800
Sponsors
Universidade Federal do Paraná
Universidade Federal do Paraná
Eligibility
Age
No minimum to 24 Hours
Inclusion criteria
Inclusion criteria: Newborns over 34 weeks of gestational age were included; newborns rooming-in accommodation; newborns whose guardians signed the Informed Consent Form.
Exclusion criteria
Exclusion criteria: Newborns with skin solution of continuity or dermatosis diagnosed at the first assessment, such as ichthyosis vulgaris, lamellar ichthyosis or atopic dermatitis; newborns with genetic or chromosomal change; newborns in phototherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increase in pH, verified through pH-metry and measured with the skin pH measurement instrument HI 99181 Portable Waterproof Skin pH Meter®, in the abdomen and thigh after bathing in the Control Group (p = 0.02 and 0.03, respectively), while in the Experimental Group there was no significant variation (p = 0.49 and 0.84, respectively), it was considered the minimum level of significance of 5% and minimum test power of 90% in the pre measurements and post-intervention. ;Erythema was more frequent in the Control Group (CG) after bathing (p <0.001), which did not occur in the Experimental Group (EG) (p = 0.86). When comparing erythema before and after bathing, there was an increase in erythema intensity after bathing in the CG (p <0.001), and a decrease in the EG (p = 0.04), such variation was obtained through the clinical evaluation performed by the same researcher. ;Before the bath, there was a greater frequency of desquamation in the Experimental Group (EG) compared to the Control Group (CG) (p = 0.04). When the peeling before and after the bath was compared, it decreased in the SG (p <0.001) and remained the same in the CG (p = 0.56), such variation was obtained through the clinical evaluation carried out by the same researcher. | — |
Secondary
| Measure | Time frame |
|---|---|
| In the frontal region, there was an increase in pH in the control and experimental groups after bathing (p <0.001), but without a statistically significant difference between them, verified through pH-metry and measured with the cutaneous pH measurement instrument HI 99181 Portable Waterproof Skin pH Meter®, even without the use of soap in this location, the minimum significance level of 5% and minimum test power of 90% in the pre- and post-intervention measurements were considered. | — |
Countries
Brazil
Contacts
Public ContactLarissa;Larissa Topan;Topan
;
Outcome results
None listed