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Assessment of pH stability and influence on tooth sensitivity after in-office dental whitening in adult patients: a double-blind randomized clinical trial

Influence and stability of pH on the sensitivity of in-office teeth whitening in adults: a double-blind randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-9k5tc4d
Enrollment
Unknown
Registered
2023-12-21
Start date
2024-01-05
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth sensitivity

Interventions

Thirty patients will be selected according to the inclusion and exclusion criteria for whitening (split mouth) with the application of two different types of whitening gels across the entire tooth sur
E06.420.750

Sponsors

Faculdade de Odontologia da Universidade Federal do Amazonas
Lead Sponsor
Faculdade de Odontologia da Universidade Federal do Amazonas
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Participants over 18 years old; both genders; with good general and oral health conditions; caries-free upper teeth and upper anterior teeth free of restorations on the buccal surface; they should also have A2 or darker colored central incisors, evaluated against a tooth value-driven visual color scale (Vita Classical, Vita BleachedGuide)

Exclusion criteria

Exclusion criteria: Pregnant women; nursing mothers; smokers; users of fixed orthodontic appliances; with pre-existing anterior restorations; presence of severe intrinsic stains (stains due to tetracycline use, fluorosis and pulpless teeth); participants with a previous history of tooth sensitivity or any associated pathology (bruxism , gingival recession, non-carious lesion with exposed dentin)

Design outcomes

Primary

MeasureTime frame
The absolute risk of tooth sensitivity (primary outcome) recorded at least once by the participant will be compared using the Mc Nemar test. The intensity of sensitivity will be compared using paired Wilcoxon statistical analysis

Secondary

MeasureTime frame
The color change (secondary outcome) with data from subjective and objective color assessment will be compared between groups using the paired Wilcoxon test. For all tests, a significance level of 5% will be considered.

Countries

Brazil

Contacts

Public ContactSheise Silva

Faculdade de Odontologia da Universidade Federal do Amazonas

sheisecerdeiradentista@gmail.com+55(92) 992719886

Outcome results

None listed

Source: REBEC (via WHO ICTRP)