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Impact of Surgery to Reduce Lung Size on the ability to breathe, the ability to exercise, and the quality of life of people with advanced Chronic Obstructive Pulmonary Disease (COPD)

Impact of Lung Volume Reduction Surgery on lung function, exercise capacity and quality of life in patients with severe COPD

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-9hyxs47
Enrollment
Unknown
Registered
2025-01-07
Start date
2025-01-10
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Interventions

Group of 30 patients with severe pulmonary emphysema enrolled in the COPD outpatient clinic of the Pulmonology Discipline at UNIFESP who underwent apical lung resection using bilateral videothoracosco
E01.370.388.250.840.830

Sponsors

Disciplina de Cirurgia Torácica Escola Paulista de Medicina - Universidade Federal de São Paulo
Lead Sponsor
Disciplina de Cirurgia Torácica Escola Paulista de Medicina - Universidade Federal de São Paulo
Collaborator

Eligibility

Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients of both genders; between 18 and 80 years of age; with severe chronic obstructive pulmonary disease (COPD) (exacerbating profile or not); clinically stable

Exclusion criteria

Exclusion criteria: Patients with bullous disease that has been removed by bullectomy; patients in a severe clinical condition; patients on mechanical ventilation

Design outcomes

Primary

MeasureTime frame
To evaluate the impact of lung volume reduction surgery on quality of life, determined using the SF-36 questionnaire before and after surgery, at routine visits at 1, 2, 6 and 12 months;To evaluate the impact of lung volume reduction surgery on exercise capacity, determined through the six-minute walk test before and after surgery, at routine visits at 1, 2, 6 and 12 months—

Secondary

MeasureTime frame
To evaluate the impact of lung volume reduction surgery on lung function, determined through spirometry before and after surgery, at routine visits at 1, 2, 6 and 12 months;To evaluate the impact of lung volume reduction surgery in the presence of symptoms, determined by the COPD assessment test before and after surgery—

Countries

Brazil

Contacts

Public ContactAndré Miotto

Universidade Federal de São Paulo

miotto@unifesp.br+55(11)914486014

Outcome results

None listed

Source: REBEC (via WHO ICTRP)