Depression, Postpartum
Conditions
Interventions
This is an observational prospective cohort study with four follow-up waves. The main exposure is the concentration of adipocytokines (adiponectin and leptin) in plasma and breast milk. Initially, pos
D06.472.699.042.249
D06.472.699.042.500
V03.175.500
Sponsors
Instituto Nacional de Saúde da Mulher da Criança e do Adolescente Fernandes Figueira/ Fundação Oswaldo Cruz
Universidade Federal do Rio de Janeiro
Universidade Federal Fluminense
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: Breastfeeding mothers up to 15 days postpartum; aged between 20 and 45 of age; exclusively breastfeeding (offering only breast milk without tea or water in the 5 days preceding entry into the study); be free from chronic non-communicable diseases such as high blood pressure and diabetes, except obesity; residing in the city of Rio de Janeiro; be free from infectious diseases such as HIV; proficient in the Portuguese language; and whose newborns had an Apgar score = 7 at the fifth minute
Exclusion criteria
Exclusion criteria: Breastfeeding mothers using antidepressant medication or other psychiatric medication; who had a twin pregnancy; who tested positive for Syphilis, Rubella, Toxoplasmosis, Cytomegalovirus, or Zika during pregnancy; who had gestational surrogacy/temporary uterine donation ('gestational carrier'); whose newborn had a premature birth, any pathology, inappropriate weight for gestational age, a diagnosis of any condition or malformation known to cause motor and/or cognitive deficits, or was admitted to a neonatal intensive care unit
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate infant neurodevelopment using the Bayley Scales of Infant and Toddler Development III (Bayley-III), analyzed on a continuous scale;To assess postpartum depression, the Edinburgh Postnatal Depression Scale (EPDS) will be used, considering that women with a score equal to or greater than 13 are classified as having depressive symptoms | — |
Secondary
| Measure | Time frame |
|---|---|
| Assess maternal and infant body composition (weight, percentage of fat, percentage of lean mass) using plethysmography, analyzed continuously | — |
Countries
Brazil
Contacts
Public ContactFernanda Rebelo
Instituto Nacional de Saúde da Mulher da Criança e do Adolescente Fernandes Figueira/ Fundação Oswaldo Cruz
Outcome results
None listed