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Evaluation of the effect of two gingival treatments in the development of gingival disease in children with heart disease

Evaluation of the effect of two periodontal treatments in the development of periodontal periodontal disease in children with heart disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-9gfmm5
Enrollment
Unknown
Registered
2013-10-30
Start date
2012-04-29
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Periodontitis

Interventions

After the initial clinical and laboratorial evaluations, the 62 patients were divided randomly into two groups of children, who were distributed according to the performed treatments: Group 1 (17 chil
Procedure/surgery

Sponsors

Universidade Estadual do Oeste do Paraná - Unioeste
Lead Sponsor
Universidade Estadual do Oeste do Paraná - Unioeste
Collaborator

Eligibility

Age
8 Years to 12 Years

Inclusion criteria

Inclusion criteria: The children should have between 8-12 years of age with chronic periodontitis, with at least 2 sites with probing depth greater than 5 mm and clinical attachment level over 2 mm, bleeding on probing and gingival inflammation to clinical examination. The teeth should perform reasonably aligned, with a minimum of 20 teeth in the arch, with the clinical examination in the buccal, lingual / palatal, mesial and distal

Exclusion criteria

Exclusion criteria: Use of antibiotics and anti-inflammatories, steroids or no steroids in the month prior to the study; periodontal treatment in the previous 6 months, and those with any chronic inflammatory disease such as rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, or Chron's disease.

Design outcomes

Primary

MeasureTime frame
Regarding periodontal treatment of children with heart disease and normal children , both shown to be effective as to the clinical data showing significant improvement , mainly those related to the parameters of dental clinic, with greater emphasis for the period of 90 days, when there was a reduction more sensitive . ;In contrast , only the gingival index (GI ) showed no improvement between periods of 90 and 180 days in group 3 and 4 ( full mouth scalling and root planning (FMSRP) , heart disease and normal respectively). Due to this fact , the IG statistically significant difference when analyzing the variations of the mean between the treatment groups scalling and root planning (SRP) and FMSRP , SRP demonstrating superiority in both the group of cardiac patients as in normal children .

Secondary

MeasureTime frame
The lipid , both treatments have proven effective with a significant improvement in virtually all parameters , with the exception of LDL in patients with heart disease who received treatment scalling and root planning (SRP) (group 1 ) and of HDL in group normal children , which were subjected to full mouth scaling and root planning (FMSRP) (group 4 ) , noting that the decline in this valor represents the worst result since the HDL has a protective factor . It is noteworthy that , despite not having been improvements in these parameters , they were kept within the desired range for age .;By studying the results obtained by the analysis of acute phase proteins , fibrinogen that had been most prominent , with significant improvement in all 4 groups , however , with the PCR improvement occurred only for those who underwent SRP , both group heart disease ( group 1) , as the normal (group 2 ) . Analyzing the proinflammatory cytokines , IL-6 was that had statistically significant improvement for all groups, but the TNFalfa had no significant result . There was no statistical difference in the mean variation between the groups when analyzed these inflammatory markers

Countries

Brazil

Contacts

Public ContactCarlos;Carlos Nassar;Nassar

Universidade Estadual do Oeste do Paraná - Unioeste;Universidade Estadual do Oeste do Paraná - Unioeste

canassar@yahoo.com;canassar@yahoo.com55(45)91013369;554591013369

Outcome results

None listed

Source: REBEC (via WHO ICTRP)