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Effect of manual therapy on the autonomic nervous system in chronic pain

Effect of manual therapy on the vagus nerve pathway in the cardiac autonomic nervous system in individuals with chronic musculoskeletal pain: a controlled and randomized study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-9g8585
Enrollment
Unknown
Registered
2020-05-22
Start date
2020-04-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal pain, Chronic Pain

Interventions

In the manual therapy group, with 30 participants, different approaches of myofascial techniques and cranial osteopathic technique will be applied in the vagus nerve path from its emergence through th
Other
E02.190.599

Sponsors

Pedro Teixeira Vidinha Rodrigues
Lead Sponsor
Pedro Teixeira Vidinha Rodrigues
Collaborator

Eligibility

Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: musculoskeletal pain for more than 3 months in any segment of the body and that fails the conditioned pain test by the cold pressor test.

Exclusion criteria

Exclusion criteria: individuals under 18 or over 60; who have a surgical procedure in the chest / spine region that prevents performing the proposed techniques; pregnant women; present rheumatological diagnosis in acute inflammatory phase; osteoporosis, primary bone tumors or not; presenting lymphedema in any member; having a pacemaker, having a cardiac arrhythmia or having a heart transplant; having eaten food and drinks containing caffeine on the day of the experiment; having drunk alcohol in the last 24 hours; use medications with a cardiac effect; unable to complete the self-administered questionnaires.

Design outcomes

Primary

MeasureTime frame
As a primary outcome, it is expected to find increased cardiac parasympathetic activity, verified by the HFms2 component (high frequency per milliseconds squared), RMSSD (square root of the mean of the square of the differences between adjacent normal RR intervals), SDRR (standard deviation of the RR interval) verified by the Heart Rate Variability, from the finding of a variation of at least 20% in the pre and post-intervention measurements.—

Secondary

MeasureTime frame
As a secondary outcome, it is expected to find decreased sensitivity to skin pressure, verified by algometry at two different points, from the observation of a variation of more than 20%.—

Countries

Brazil

Contacts

Public ContactPedro Rodrigues

Centro Universitário Augusto Motta

pvidinha@hotmail.com+55(22)25224489

Outcome results

None listed

Source: REBEC (via WHO ICTRP)