Chronic Periodontitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Participants with type 2 diabetes mellitus and periodontitis stages II and III, with a minimum age of 30 years and at least fourteen teeth present in the oral cavity, and who agree to participate in the research through an informed consent form will be included.
Exclusion criteria
Exclusion criteria: The following individuals will be excluded from the study: with a history of allergy to pollen or any product of apiarian origin; carriers of diseases with changes in the immune system; smokers; pregnant and lactating women; who have undergone periodontal treatment in the last 6 months; who have undergone antimicrobial and anti-inflammatory therapy in the last 3 months; who use anticoagulant and platelet antiaggregant; with dental implants; with glycated hemoglobin greater than or equal to 9% and/or fasting glucose greater than or equal to 250mg/dl; who change their diabetes medication during the study period; under 30 years old.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Probing pocket depht. Evaluate the pocket depth before the treatment and 60 and 90 days after the treatment using periodontal probing with a periodontal probe UNC 15 mm. The expected result is a greater reduction of the probing depth in the test group than in the control group. | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical attachment level. Evaluate the clinical attachment level before the treatment and 60 and 90 days after the treatment using periodontal probing with a periodontal probe UNC 15 mm. The expected result is a greater reduction of the clinical attachment level in the test group than in the control group.;Bleeding on probing. Evaluate the percentual of sites with bleeding on probing before the treatment and 60 and 90 days after the treatment using periodontal probing with a periodontal probe UNC 15 mm. The expected result is a greater reduction of the bleeding on probing percentual in the test group than in the control group.;Glycated hemoglobin (HbA1c). Evaluate the glycated hemoglobin levels before the treatment and 60 and 90 days after the treatment through the blood. The expected result is a greater reduction of the glycated hemoglobin measure in the test group than in the control group.;Fasting blood glucose. Evaluate the fasting blood glucose levels before the treatment and 60 and 90 days after the treatment through the blood. The expected result is a greater reduction of the fasting blood glucose measure in the test group than in the control group.;C reactive protein (CRP). Evaluate the CRP before the treatment and 60 and 90 days after the treatment through the blood. The expected result is a greater reduction of the CRP measure in the test group than in the control group. | — |
Countries
Brazil
Contacts
Universidade Federal de Minas Gerais