Oral and oropharyngeal cancer, oral mucositis
Conditions
Interventions
All research participants (total of 60 patients) will initially undergo a clinical evaluation lasting up to 30 minutes when general pertinent research information such as age, gender, tumor location,
Dietary supplement
G07.203.300.456
Sponsors
Faculdade de Odontologia de Piracicaba - UNICAMP
Fundação Antônio Prudente
Eligibility
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: olunteers with primary malignant neoplasms in the mouth or oropharynx; submitted to 2D, 3D or IMRT adjuvant radiotherapy, exclusive or associated with chemotherapy
Exclusion criteria
Exclusion criteria: Patients previously irradiated in the head and neck region; patients who present some type of discomfort or a history of propolis allergy; patients who do not have minimum clinical conditions for use of propolis voluntarily
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected that the organic propolis solution provide the absence or reduction of mucositis in patients undergoing head and neck radiotherapy. This outcome will be obtained through weekly oral clinical evaluations of the patient during cancer treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected that the organic propolis solution to modulate oral microbiota and decrease inflammatory cytokines. This outcome will be evaluated by obtaining 3 to 4 oral swab samples from each patient during cancer treatment. | — |
Countries
Brazil
Contacts
Public ContactMarcio Lopes
Faculdade de Odontologia de Piracicaba - UNICAMP
Outcome results
None listed