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Clinical Study Toothpaste base Rosemary on Plaque and Saliva Bacterium

Clinical evaluation of the antimicrobial activity of the dentifrice the basis of Rosmarinus officinalis Linn extract. (rosemary) on the biofilm and saliva S. mutans

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
REBEC
Registry ID
RBR-9f3ctb
Enrollment
Unknown
Registered
2015-10-22
Start date
2014-02-08
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingivitis, Dental cavity

Interventions

Experimental group: 55 volunteers of both sexes, healthy, significant periodontal disease-free (acute gingivitis, periodontal pocket) and tooth decay, will be examined in the mouth on the gum sagramen
Other

Sponsors

UFPE-Universidade Federal de Pernambuco
Lead Sponsor
UFRPE-Universidade Federal Rural de Pernambuco
Collaborator

Eligibility

Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Healthy volunteers; both genders; aged 18 to 45 years; minimum of 20 healthy teeth in the mouth; without systemic diseases; without the use of drugs; healthy oral condition Sample size : 110 patients

Exclusion criteria

Exclusion criteria: Smoking volunteers; pregnant women; people with periodontal disease or decay; carriers of important systemic diseases; drug users; people with braces

Design outcomes

Primary

MeasureTime frame
Decreased gingival bleeding in the 30-day period, verified by measuring through the Gingival Bleeding Index Ainamo & Bay (1975), starting from the realization of a range of at least 18% in pre and post measurements intervention

Secondary

MeasureTime frame
Reducing the amount of plaque in the 30-day period, verified by measuring through Turesky Board Index (1970) starting from the realization of a range of at least 14% in pre and post intervention measurements

Countries

Brazil

Contacts

Public ContactMarcela Valones

UFPE-Universidade Federal de Pernambuco

mavalona@globo.com+55(81)992528488

Outcome results

None listed

Source: REBEC (via WHO ICTRP)