Atrophy of the alveolar residual ridge
Conditions
Interventions
This is a randomized clinical trial of equivalence and parallel groups and blind (evaluator). Randomization by type of treatment will be carried out using the patient unit as a base, the randomization
Sponsors
Faculdade de Odontologia da Universidade Federal de Pelotas/RS
M3 Health Industria e Comercio de Produtos Medicos, Odontologicos e Correlatos S.a.
Eligibility
Inclusion criteria
Inclusion criteria: Patients of both sexes; in a balanced number without age criteria; no self reported systemic health problems; do not use any medication in the last 3 months that affects the immune response; bone quality without the need for local bone grafting; availability to attend Faculty of Dentistry at the Federal University of Pelotas
Exclusion criteria
Exclusion criteria: Patients who smoke; severe diabetes; blood disorders; hemorrhagic diastasis; drug-induced anticoagulation; rheumatoid arthritis; osteogenesis imperfecta; HIV; use of immunosuppressive medications; history of radiotherapy to the head or neck region, history of previous oral implant insertion; patients who have undergone treatment with bisphosphonates in the last 12 months; if female, not pregnant or lactating; with constant use or with a medical history marked by chronic use of analgesics; anti-inflammatories and psychotropic drugs; need for bone grafting at the implant site
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of the release of cytokines (IL-1ß, IL-6, IL-10, IL-17, TNF-a) during the implant healing phase and 6 months after the installation of overdentures. | — |
Secondary
| Measure | Time frame |
|---|---|
| Monitoring of clinical parameters through examinations of visible plaque index, gingival bleeding index, presence of calculus, probing depth index and implant stability quotient.;Evaluate quality of life and chewing function indicators before loading, during the first year of transition from complete dentures to overdentures and after 2 and 3 years.;Monitor the peri-implant bone level and posterior resorption of the mandibular ridge after 1, 2 and 3 years of occlusal loading.;Monitor the circumferential bone level of the implants at 1 and 3 years.;Evaluate the success and survival of implants.;Describe prosthetic complications over 3 years depending on. | — |
Countries
Brazil
Contacts
Public ContactLucas da Silva
Faculdade de Odontologia da Universidade Federal de Pelotas/RS
Outcome results
None listed