Disorders of the teeth and their supporting structures impacted teeth
Conditions
Interventions
This is a randomized controlled clinical trial, with four arms and triple-blind. A total of 60 teeth and 41 patients met the eligibility criteria and were probabilistically allocated to one or another
15 teeth in this group). 2 – Preoperative antibiotic therapy (2 grams of amoxicillin was administered 1 hour before the surgical procedure, 15 teeth in this group). 3 – Postoperative antibiotic therap
Sponsors
Obras Sociais e Educacionais de Luz
Universidade de Santo Amaro
Eligibility
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Patients of both genders; aged between 18 and 35 years; who do not present Local or Systemic Pathologies; having impacted lower third molars that require Osteotomy and/or Odontosection
Exclusion criteria
Exclusion criteria: Patients who are allergic to the medications used in the study; individuals who were not interested in participating in the research; diagnosis of Cardiac Diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: An improvement is expected in the postoperative period of patients who received antibiotic therapy before third molar surgery, as assessed by pain measurements and the presence of infection, with at least a 5% variation for the test groups. Data collected on the day of the intervention and at different periods after the intervention.;Outcome found 1: It was observed that the groups in which antibiotics were administered postoperatively, both with and without preoperative administration, obtained the best values for pain and presence of infection, with a 25% lower infection rate compared to the placebo (control) group and 20% lower pain perception in the first 6 hours postoperatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 2: Given the methodology used, we expect to find lower measurements of edema and trismus following the removal of impacted third molars in the groups that received antibiotic therapy pre- and/or postoperatively. ;Outcomes found: It was observed that the group that received antibiotic therapy pre- and postoperatively showed a significant reduction in trismus compared to the placebo group following the removal of third molars. The results regarding edema were not significant. | — |
Countries
BR
Contacts
Public ContactKaique Silva
Universidade de Santo Amaro
Outcome results
None listed