Skin alterations due to chronic exposure to non-ionizing radiation unspecified/photo-aging
Conditions
Interventions
Eleven patients will undergo a split-face study of a single randomized session, in one side of the face, standard phenol-croton oil peeling using Septisol® (standard control), and the other side of th
Procedure/surgery
T14.0
Sponsors
Hospital Heliópolis
Hospital Heliópolis
Eligibility
Sex/Gender
Female
Age
50 Years to 70 Years
Inclusion criteria
Inclusion criteria: phototypes between I and III according to Fitzpatrick's; photoaging according to Global Photoaging Score Types III and IV; non smoking
Exclusion criteria
Exclusion criteria: Recent history of skin lesions or surgeries in the past three months; Medical history of heart disease and/or arrhythmias of any nature, kidney failure or hepatic disease; Medical history of Asthma or Chronic Obstructive Pulmonary Disease (COPD); Medical history of Iron Overload (Hemochromatosis); Use of oral Isotretinoin (13-cis-retinoic acid) in the past six months; Patients with immunosuppressive Conditions, Decompensated Diabetes or Systemic Conditions which interfere on the healing/scaring process such as Malnutrition and Neoplasms; Personal history of keloid. Smoking. Collagenose. Pregnancy or Breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We expect that there is no difference between the groups. Clinical evaluation based on a scale of improvement of wrinkles in a 5-point scale: 0 (no improvement) to 4 (complete improvement. ;Expected outcome: > 2 for both arms. | — |
Secondary
| Measure | Time frame |
|---|---|
| We expect that there is no difference between the groups. Patient opinion evaluation based on a scale of improvement of wrinkles in a 5-point scale: 0 (no improvement) to 4 (complete improvement.;Expected outcome: > 2 for both arms. | — |
Countries
Brazil
Contacts
Public ContactCarlos;Daniella Wambier;Curi
Dermatology Department - Yale University;Hospital Heliópolis
Outcome results
None listed