Skin Aging
Conditions
Interventions
This study will be a randomized, double-blind, controlled clinical trial. Patients will be randomized into four groups: Group 1 - control - will not receive treatment - 20 patients. These patients wil
Sponsors
Faculdade de Odontologia da Universidade de São Paulo (Fousp)
Faculdade de Odontologia da Universidade de São Paulo (Fousp)
Eligibility
Age
35 Years to 70 Years
Inclusion criteria
Inclusion criteria: Males and females aged 35 to 70 years; in good general health; willing to adhere to the study protocol; presenting a chief complaint of aesthetic dissatisfaction with their lips; and pronounced nasolabial folds
Exclusion criteria
Exclusion criteria: Previous application of fillers or botulinum toxin in the region at any given moment; the possibility and/or presence of pregnancy; active oncologic treatment; and other conditions that lead to alterations in circulatory and or metabolic systems
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: Reduction or increase (in millimeters) of facial lines in the perioral region, assessed at four time points (before, immediately after, 1 month, and 3 months post-intervention).;Finding outcome 1: There were statistically significant improvements in the laser-treated group (Friedman test), demonstrating the treatment effect over time (T0 vs. T1, T2, T3). | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcomes are expected | — |
Countries
Brazil
Contacts
Public ContactPaula Carvalho
Faculdade de Odontologia da Universidade de São Paulo (Fousp)
Outcome results
None listed