Knee Osteoarthritis
Conditions
Interventions
Group 1 (25 patients): total prosthesis of the knee and at the end, before the closure of the capsule articular, topical application of 6 ml of platelet-rich plasma, prepared from 20 ml of the patient
Drug
Biological/vaccine
Procedure/surgery
Sponsors
Irmandade Santa Casa de Londrina
Irmandade Santa Casa de Londrina
Eligibility
Inclusion criteria
Inclusion criteria: Volunteers with knee osteoarthritis Severa and indication of total knee prosthesis for treatment
Exclusion criteria
Exclusion criteria: inflammatory diseases; hematological diseases; great deformities; use of anticoagulants previously
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| expected outcome is reduced bleeding, the method is by collecting blood samples at the time of surgery, 24 and 48 hours after surgery and the presentation is by comparing the drop in hemoglobin dosage levels;expected outcome is less postoperative pain, measurement methods are visual scale of pain with zero to ten notes to the sensation of pain, need for morphine to control the pain | — |
Secondary
| Measure | Time frame |
|---|---|
| improvement in knee function, through questionnaire Western Ontario e McMaster Universities Osteoartrite Index validated for the Portuguese language applied in pre operative and after 2 months, 6 months, 12 months and 24 months | — |
Countries
Brazil
Contacts
Public ContactJoao Paulo Guerreiro
Uniort.e
Outcome results
None listed