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Discovery of proteins that differentiate health and disease around dental implants

The searching for novel biomarkers for the diagnosis of peri-implant diseases using proteomic approaches

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-99xvpph
Enrollment
Unknown
Registered
2022-12-19
Start date
2022-08-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peri-Implantitis

Interventions

This observational prospective study will analyze a population rehabilitated with one or more dental implants who have been followed for at least 10 years in a University setting in Brazil. Clinical a
V03.175.500

Sponsors

Universidade Estadual de Maringá
Lead Sponsor
International Team for Implantology
Collaborator

Eligibility

Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with one or more dental implants with at least 10 years in function treated at Dental Clinic of the State University of Maringá

Exclusion criteria

Exclusion criteria: Medical history that includes serious medical conditions or communicable diseases; Use of immunosuppressive drugs, bisphosphonates or steroids in the last 5 years; Antibiotic therapy or oral prophylactic procedures within the previous 3 months; Conditions that require prophylactic antibiotic coverage prior to dental treatment; Pregnancy or lactation; Subjects who underwent non-surgical treatment for peri-implant disease in the last 6 months; Subjects who underwent surgical treatment for Peri-implantitis in the last two years; Sites with implant-supported rehabilitations with little marginal adaptation and inadequate access to hygiene.

Design outcomes

Primary

MeasureTime frame
The proteins around implants from healthy participants are expected to be different from the proteins from sick participants.;The salivary proteins of participants with healthy implants are expected to be different from those of participants with diseased implants.

Secondary

MeasureTime frame
Secondary outcomes are not expected.

Countries

Brazil

Contacts

Public ContactMaurício Araújo

Universidade Estadual de Maringá

odomar@hotmail.com+55(44)30119052

Outcome results

None listed

Source: REBEC (via WHO ICTRP)