FindTrial
Sign In

Assessment of postoperative events after Ozonetherapy in lower third molar Extractions

Effects of Ozonetherapy in the postoperative period of lower third molar Extraction – pilot, randomized, blind, split-mouth clinical study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-99qvrnj
Enrollment
Unknown
Registered
2024-08-19
Start date
2024-08-20
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Localized edema

Interventions

This is a randomized, blinded, split mouth clinical pilot study. Fifteen patients who meet the eligibility criteria will be randomly allocated to both groups. Since this is a split mouth study, the in
E06.892

Sponsors

Instituto de Ciência e Tecnologia - Campus de São José dos Campos – Universidade Estadual Paulista
Lead Sponsor
Instituto de Ciência e Tecnologia - Campus de São José dos Campos – Universidade Estadual Paulista
Collaborator

Eligibility

Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Female and male patients, need of third molar extraction; regardless of gender; patients who have not used analgesics or anti-inflammatories in the last 15 days; have teeth in opposing semi-included or included hemi-arches, meeting the same classification as Pell & Gregory (1933); aged between 18 and 30 years; who agree to participate in the research voluntarily, being aware of the risks and benefits, and sign the Free and Informed Consent Form (TCLE).

Exclusion criteria

Exclusion criteria: Patients who present local or systemic changes that contraindicate the procedure; patients undergoing drug treatments that interfere with the methodology; erupted lower third molars; patients allergic to anesthetics and medications; patients with contraindications to the use of ozone therapy; smoking patients; pregnant or lactating patients

Design outcomes

Primary

MeasureTime frame
It is expected to find a decrease in immediate and mediate postoperative pain, with a minimum variation of 5%, when patients undergo treatment in the ozone group, an assessment using the visual pain scale—

Secondary

MeasureTime frame
It is expected to find a decrease in postoperative edema, at least 5%, when compared to the baseline measurement, a comparison using the standard of Ustün et al., (2003), when patients undergo treatment in the ozone group.;It is expected to find a greater mouth opening in the postoperative period, when compared to pre-surgical measurement, in patients undergoing treatment in the ozone group—

Countries

Brazil

Contacts

Public ContactMichelle de Moraes

Instituto de Ciência e Tecnologia - Universidade Estadual Paulista "Júlio de Mesquita Filho"

michelle.bianchi@unesp.br+55(12) 39479000

Outcome results

None listed

Source: REBEC (via WHO ICTRP)