Chronic Obstructive Pulmonary Disease
Conditions
Interventions
40 subjects with chronic obstructive pulmonary disease. 20 subjects will receive 1 capsule of 3 mg melatonin and 20 subjects will receive 1 capsule placebo per day, two hours before bed at night and t
Other
HP3.073.433.101
Sponsors
Universidade Federal do Ceará Programa de Pós Graduação em Ciencias Médicas
Centro Universitário Estácio do Ceará
Hospital Universitário Walter Cantídio Universidade Federal do Ceará
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Selection criteria for rehabilitation program will includ patients from the Pulmonology Service of the WCUH-FUC; of both sexes; above 18 years; with medical diagnosis of Chronic obstructive pulmonary disease based on the Global obsctructive lung disease guideline; stability with no exacerbations or worsening of respiratory symptoms; no increased use of rescue medication and ability to mobilize independently
Exclusion criteria
Exclusion criteria: The exclusion criteria for rehabilitation program will be the patient will submit to exacerbation of Chronic obstructive pulmonary disease; orthopedic or neurologic impairment that might render the subjects incapable of completing the exercise training; patients who not continue rehabilitation for 12 weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sleep quality improvement is expected to be assessed by an actimeter worn on the wrist for seven days before and after treatment.;Through digital manovacuometry it is expected to observe improvement of respiratory muscle strength from the finding of a variation of at least 5% in pre and post-intervention measurements.;It is expected to improve peripheral muscle strength after intervention assessed by hand grip dynamometer in COPD patients undergoing Pulmonary Rehabilitation Program. | — |
Secondary
| Measure | Time frame |
|---|---|
| There will probably be improvement in daytime sleepiness that will be assessed by the Epworth scale.;An improvement in the anxiety and depression levels observed in these individuals is expected, observed by specific questionnaires.;There is an expectation of improvement in functional capacity that will be assessed by the exercise test by an increase of at least 80 meters in the six-minute walk test in Chronic obstructive pulmonary disease patients following the participation of the Pulmonary Rehabilitation Program. | — |
Countries
Brazil
Contacts
Public ContactSoraya Viana
Universidade Federal do Ceará Programa de Pós Graduação em Ciencias Médicas
Outcome results
None listed