Overweight and obesity
Conditions
Interventions
Experimental group: 20 subjects supplemented with herbal extract containing Yerba Mate (112mg), Guarana (95mg), Damiana (36mg)before breakfast and lunch. Placebo group: 20 subjects supplemented with c
Dietary supplement
SP6.051.227
Sponsors
Universidade Federal de Goiás
Universidade São Francisco
Eligibility
Sex/Gender
Female
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: BMI 25 and 39,9 kg/m²;20 Sedentary women and healthy;Aged 20 to 50 years
Exclusion criteria
Exclusion criteria: Unavailability of one day/ week for the study day;participants with autoimmune liver kidney or hypothyroidism diseases; gastrointestinal symptoms requiring treatment; bariatric surgery;participants of a food restriction program or that practiced diet in the last 12 months to lose or control weight;without use current adherence to a specific food avoidance diet;taking medication or nutritional supplements known to affect appetite or weight;taking medication immunosuppressive or insulin; being pregnant or planning to become pregnant or breastfeeding; menopause;chronic alcoholics;history of anaphylaxis to food; food allergies, including caffeine or other compound present in the supplement and any of the study foods;intolerance or allergy to lactose
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in energy intake at breakfast and lunch assessed by weighing the food leftover, from the finding of a difference of at least 5% between groups. Reduction in the area under the curve for the ghrelin concentrations after breakfast and lunch assessed by biochemical analysis (multiplex system), based on the statement of a difference of at least 20% in both groups. Significant reduction in the area under the curve for acylated ghrelin concentration, based on the statement of the difference between groups of 177.41% only after lunch.;Increasing the area under the curve for concentrations of GLP-1 after breakfast and lunch evaluated by biochemical analysis (multiplex system), from finding a difference of at least 20% between groups. Significant increase in the area under the curve for GLP-1 concentration, based on the statement of the difference between groups of 625% only after breakfast.;Significant increase in the area under the curve for GLP-1 concentration, based on the statement of the difference between groups of 625% only after breakfast. | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction in glucose concentrations after breakfast and lunch evaluated through digital glucometer from the observation that a difference of at least 5% between groups. Significant reductions in glucose concentrations between 90 and 210 minutes after breakfast, based on the statement of the 5% difference between the groups. Reducing the feeling of hunger after breakfast and lunch assessed by visual analog scale, based on the statement of difference of at least 10% between groups. | — |
Countries
Brazil
Contacts
Public ContactMarina Celestino
Universidade Federal de Goiás
Outcome results
None listed