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Impact of physical exercise on heart and skeletal muscle health

Evaluation of the effect of a physical exercise program on the muscular and vascular health of elderly individuals

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-9857xj3
Enrollment
Unknown
Registered
2024-07-12
Start date
2024-08-15
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anxiety

Interventions

This is a randomized, controlled, crossover study. Experimental group training at different exercise intensities: 20 healthy young individuals and 20 individuals aged 60 years or older. A control grou

Sponsors

Universidade Federal do Rio de Janeiro Campus Macaé
Lead Sponsor
Universidade Federal do Rio de Janeiro Campus Macaé
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Elderly people (over 60 years of age); male and female sex; high triglycerides (>150 mg/dL); reduced HDL-cholesterol ( 102 cm for men and > 88 cm for women; hypertensive (systolic pressure above 130 mm Hg and diastolic pressure above 90 mm Hg); and increased fasting blood glucose (> 100 mg/dL) or diagnosed with type II diabetes mellitus; with or without a diagnosis of common mental disorder (anxiety and/or depression). Young people (over 18 years old); male and female sex; sedentary or physically active; no musculoskeletal diseases; with or without the presence of risk factors for cardiovascular diseases; with or without a diagnosis of common mental disorder (anxiety and/or depression)

Exclusion criteria

Exclusion criteria: Osteoarthritis and rheumatoid arthritis; infected with HIV virus; use of drugs that interfere with the vascular and nervous system

Design outcomes

Primary

MeasureTime frame
We will seek to evaluate glucose, triglycerides and cholesterol levels, using colorimetric methods. Using this method, it is possible to evaluate biochemical parameters in the blood. The unit of measurement will be in milligrams per deciliters. We expect to see a reduction in glucose, triglycerides and cholesterol levels after a strength training session when compared to the pre-exercise assessment;We will seek to assess levels of anxiety, depression, mood, sleep quality and cognition, using questionnaire application methods to assess levels of anxiety, depression, mood, sleep quality and cognition through scores (number) generated by each questionnaire applied. We expect to observe a reduction in anxiety and depression scores and an increase in mood, sleep quality and cognition scores after a strength training session compared to questionnaire scores assessed before strength training;We will seek to evaluate blood pressure, blood flow and heart rate, using automatic pneumatic cuff methods with a digital screen to evaluate these hemodynamic parameters. Using this method, it is possible to generate numerical values ??for blood pressure in millimeters of mercury, blood flow speed in centimeters per second and heart rate in beats per second. We expect to see a reduction in blood pressure and heart rate and increases in blood flow after a strength training session when compared to the pre-exercise assessment;We will seek to evaluate the muscular strength of the lower and upper limbs, using maximum load test methods on weight training equipment. Using this method, it is possible to evaluate muscular strength through the number of maximum repetitions performed on each piece of equipment for a given load added to the equipment. The unit of measurement for the load will be in kilograms. We expect to see an increase in muscle strength after a strength training session when compared to the assessment before exercise

Secondary

MeasureTime frame
We will seek to assess levels of anxiety, depression, mood, sleep quality and cognition, using questionnaire application methods to assess levels of anxiety, depression, mood, sleep quality and cognition through scores (number) generated by each questionnaire applied. We expect to observe a reduction in anxiety and depression scores and an increase in mood, sleep quality and cognition scores after 4, 8 and 12 weeks of strength training compared to questionnaire scores assessed before strength training;We will seek to evaluate blood pressure, blood flow and heart rate, using automatic pneumatic cuff methods with a digital screen to evaluate these hemodynamic parameters. Using this method, it is possible to generate numerical values ??for blood pressure in millimeters of mercury, blood flow speed in centimeters per second and heart rate in beats per second. We expect to see a reduction in blood pressure and heart rate and increases in blood flow after 4, 8 and 12 weeks of strength training when compared to the pre-exercise assessment;We will seek to evaluate the muscular strength of the lower and upper limbs, using maximum load test methods on weight training equipment. Using this method, it is possible to evaluate muscular strength through the number of maximum repetitions performed on each piece of equipment for a given load added to the equipment. The unit of measurement for the load will be in kilograms. We expect to see an increase in muscle strength after 4, 8 and 12 weeks of strength training when compared to the pre-exercise assessment;We will seek to evaluate glucose, triglycerides and cholesterol levels, using colorimetric methods. Using this method, it is possible to evaluate biochemical parameters in the blood. The unit of measurement will be in milligrams per deciliters. We expect to observe a reduction in glucose, triglycerides and cholesterol levels after 4, 8 and 12 weeks of strength training when compared to the pre-exercise assessment

Countries

Brazil

Contacts

Public ContactGustavo Oliveira

Universidade Federal do Rio de Janeiro

gvo.vieira@gmail.com+55(22)999643431

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 3, 2026