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Effect of the use of L-Arginine, Caffeine or Creatine supplements associated with physical activity in women with Polycystic Ovary Syndrome with Metabolic Syndrome

Thermogenic Adaptation in Patients with Polycystic Ovarian Syndrome with Metabolic Syndrome Supplemented by Chronology with L-Arginine, Caffeine or Creatine and Training Resisted Exercise - Randomized Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-9832jt
Enrollment
Unknown
Registered
2018-12-12
Start date
2019-02-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy population containing Polycystic Ovarian Syndrome

Interventions

The production will be done by 100 women of childbearing age (20 to 35 years old), with Polycystic Ovary Syndrome and Metabolic Syndrome, being supplemented, L-arginine (80 mg.kg -1), creatine (80 mg.
weight and height
bioimpedance
strength test (manual, scapular, lumbar and lower limb)
unipodal equilibrium test on the platform and vertical propulsion on the platform
abdominal muscle resistance test and flexion of the test of tolerance to fatigue and state of humor. 3 day: Evaluation of resting metabolic rate, maximum Vo2 and cardiac function 4 day: Biopsy of ab
Procedure/surgery
Dietary supplement
Other
G07.203.300.456
G11.427.410.698.277
E01.370.225.500.384.100.119

Sponsors

Universidade Federal de Mato Grosso
Lead Sponsor
Instituto Tropical de Medicina Reprodutiva e Menopausa
Collaborator
Hospital Universitário Julio Muller
Collaborator

Eligibility

Sex/Gender
Female
Age
20 Years to No maximum

Inclusion criteria

Inclusion criteria: Women with PCOS who present a metabolic syndrome, with a total age of 20-35 years in the period of the research, who are sedentary or do not practice more than two days of physical exercise, will be selected in the INTRO database , and to sign the Free and Informed Consent Form (TCLE).

Exclusion criteria

Exclusion criteria: Women who are not within the age range standardized by this research, ie obese women with SOP or SM, women who use steroids or other drugs that may interfere with metabolism, hyperprolactinemia, hypo / hyperthyroidism, congenital adrenal hyperplasia classical and non-classical Cushing's disease and tumors of ovary or adrenal secreting androgen women who are pregnant.

Design outcomes

Primary

MeasureTime frame
The presentation of the expected outcome is the attenuation of the symptoms that characterize the Polycystic Ovarian Syndrome, through the improvement in the symptomatology of these affected women, verified through the supplements researched.—

Secondary

MeasureTime frame
Secondary outcomes are not expected—

Countries

Brazil

Contacts

Public ContactCarlos Fett

Universidade Federal de Mato Grosso

fettcarlos@gmail.com+556536158833

Outcome results

None listed

Source: REBEC (via WHO ICTRP)