Activating Appliances
Conditions
Interventions
This clinical study aims to evaluate the perception of pain, chewing quality and the concentration of inflammatory cytokines in individuals undergoing orthodontic treatments with self-ligating fixed a
T1 (24 hours later)
T2 (48 hours later)
T3 (72 hours later) and T4 (7 days later). At each of these moments the gingival crevicular fluid of the upper incisors will be collected to compare the concentrations of pro-inflammatory (Interleukin
Device
E05.318.308.980
Sponsors
Aline Medeiros
Aline Medeiros
Eligibility
Inclusion criteria
Inclusion criteria: age range from 12 to 35 years old; need for orthodontic treatment; with dental crowding between 4 and 8 mm in the upper arch; with proper oral hygiene; no caries; both sexes.
Exclusion criteria
Exclusion criteria: symptoms of temporomandibular joint dysfunction; chronic use of anti-inflammatory drugs or antibiotics; with periodontal disease with generalized probing depth of 3 mm at the test sites; with craniofacial anomalies; wearing orthodontic devices that cause discomfort.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1:To assess pain levels, inflammatory cytokines, and chewing quality during treatment with different types of orthosontic appliances. Pain perception will be assessed by visual analogue scale, chewing quality assessed by the Chewing Quality Assessment Questionnaire (QAQM) and cytokine levels assessed by the Flow Cytometry Test (BD ™ CBA). Orthodontic treatments with aesthetic aligners are expected to have lower pain, better chewing quality and less inflammatory cytokines. Levels of 5% will be adopted for pre and post intervention measurements. | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcomes are expected | — |
Countries
Brazil
Contacts
Public ContactAline;Aline Fonseca;Fonseca
Fundação Heminio Ometto;Fundação Heminio Ometto
Outcome results
None listed